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 Select your preferred language English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog English English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog Translation is unavailable for Internet Explorer Cedars-Sinai Home 1-800-CEDARS-1 1-800-CEDARS-1 Close Find a Doctor Locations Programs & Services Health Library Patient & Visitors Community My CS-Link RESEARCH clear Go Close Navigation Links Academics Faculty Development Community Engagement Calendar Research Research Areas Research Labs Departments & Institutes Find Clinical Trials Research Cores Research Administration Basic Science Research Clinical & Translational Research Center (CTRC) Technology & Innovations News & Breakthroughs Education Graduate Medical Education Continuing Medical Education Graduate School of Biomedical Sciences Professional Training Programs Medical Students Campus Life Office of the Dean Simulation Center Medical Library Program in the History of Medicine About Us All Education Programs Departments & Institutes Faculty Directory Di Vizio Lab Back to Di Vizio Lab Lab Members Publications Research Areas 
  Publications See a complete PubMed list of publications by Dolores Di Vizio, MD, PhD. Selected Key Publications Vagner T, Spinelli C, Minciacchi VR, Balaj L, Zandian M, Conley A, Zijlstra A, Freeman MR, Demichelis F, De S, Posadas EM, Tanaka H, Di Vizio D. Large extracellular vesicles carry most of the tumour DNA circulating in prostate cancer patient plasma. J Extracell Vesicles. 2018 Aug 7;7(1):1505403. https://www.tandfonline.com/doi/full/10.1080/20013078.2018.1505403. Zijlstra A, Di Vizio D.
% Publications - Di Vizio Lab Cedars-Sinai Skip to content Close Select your preferred language English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog English English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog Translation is unavailable for Internet Explorer Cedars-Sinai Home 1-800-CEDARS-1 1-800-CEDARS-1 Close Find a Doctor Locations Programs & Services Health Library Patient & Visitors Community My CS-Link RESEARCH clear Go Close Navigation Links Academics Faculty Development Community Engagement Calendar Research Research Areas Research Labs Departments & Institutes Find Clinical Trials Research Cores Research Administration Basic Science Research Clinical & Translational Research Center (CTRC) Technology & Innovations News & Breakthroughs Education Graduate Medical Education Continuing Medical Education Graduate School of Biomedical Sciences Professional Training Programs Medical Students Campus Life Office of the Dean Simulation Center Medical Library Program in the History of Medicine About Us All Education Programs Departments & Institutes Faculty Directory Di Vizio Lab Back to Di Vizio Lab Lab Members Publications Research Areas Publications See a complete PubMed list of publications by Dolores Di Vizio, MD, PhD. Selected Key Publications Vagner T, Spinelli C, Minciacchi VR, Balaj L, Zandian M, Conley A, Zijlstra A, Freeman MR, Demichelis F, De S, Posadas EM, Tanaka H, Di Vizio D. Large extracellular vesicles carry most of the tumour DNA circulating in prostate cancer patient plasma. J Extracell Vesicles. 2018 Aug 7;7(1):1505403. https://www.tandfonline.com/doi/full/10.1080/20013078.2018.1505403. Zijlstra A, Di Vizio D.
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Size matters in nanoscale communication. Nat Cell Biol. 2018 Mar;20(3):228–230. https://www.nature.com/articles/s41556-018-0049-8. Soekmadji C, Hill AF, Wauben MH, Buzás EI, Di Vizio D, Gardiner C, Lötvall J, Sahoo S, Witwer KW. Towards mechanisms and standardization in extracellular vesicle and extracellular RNA studies: results of a worldwide survey. J Extracell Vesicles. 2018 Oct 24;7(1):1535745. https://www.tandfonline.com/doi/full/10.1080/20013078.2018.1535745.
Size matters in nanoscale communication. Nat Cell Biol. 2018 Mar;20(3):228–230. https://www.nature.com/articles/s41556-018-0049-8. Soekmadji C, Hill AF, Wauben MH, Buzás EI, Di Vizio D, Gardiner C, Lötvall J, Sahoo S, Witwer KW. Towards mechanisms and standardization in extracellular vesicle and extracellular RNA studies: results of a worldwide survey. J Extracell Vesicles. 2018 Oct 24;7(1):1535745. https://www.tandfonline.com/doi/full/10.1080/20013078.2018.1535745.
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Natalie Lopez 2 minutes ago
Reis-Sobreiro M, Chen JF, Novitskaya T, You S, Morley S, Steadman K, Kaur Gill NK, Eskaros A, Rotine...
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Reis-Sobreiro M, Chen JF, Novitskaya T, You S, Morley S, Steadman K, Kaur Gill NK, Eskaros A, Rotinen M, Chu CY, Chung LWK, Tanaka H, Yang W, Knudsen BS, Tseng HR, Rowat AC, Posadas EM, Zijlstra A, Di Vizio D, Freeman MR. Emerin deregulation links nuclear shape instability to metastatic potential. Cancer Res. 2018 Nov 1;78(21):6086-6097. https://aacrjournals.org/cancerres/article/78/21/6086/631793/Emerin-Deregulation-Links-Nuclear-Shape Minciacchi VR, Zijlstra A, Rubin MA, Di Vizio D. Extracellular vesicles for liquid biopsy in prostate cancer: where are we and where are we headed? Prostate Cancer Prostatic Dis.
Reis-Sobreiro M, Chen JF, Novitskaya T, You S, Morley S, Steadman K, Kaur Gill NK, Eskaros A, Rotinen M, Chu CY, Chung LWK, Tanaka H, Yang W, Knudsen BS, Tseng HR, Rowat AC, Posadas EM, Zijlstra A, Di Vizio D, Freeman MR. Emerin deregulation links nuclear shape instability to metastatic potential. Cancer Res. 2018 Nov 1;78(21):6086-6097. https://aacrjournals.org/cancerres/article/78/21/6086/631793/Emerin-Deregulation-Links-Nuclear-Shape Minciacchi VR, Zijlstra A, Rubin MA, Di Vizio D. Extracellular vesicles for liquid biopsy in prostate cancer: where are we and where are we headed? Prostate Cancer Prostatic Dis.
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Julia Zhang 1 minutes ago
2017 Sep;20(3):251–258. https://www.nature.com/articles/pcan20177. Minciacchi VR, Spinelli C, Rei...
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2017 Sep;20(3):251–258. https://www.nature.com/articles/pcan20177. Minciacchi VR, Spinelli C, Reis-Sobreiro M, Cavallini L, You S, Zandian M, Li X, Chiarugi P, Adam RM, Posadas EM, Viglietto G, Freeman MR, Cocucci E, Bhowmick NA, Di Vizio D. MYC mediates large oncosome-induced fibroblast reprogramming in prostate cancer. Cancer Res. 2017 May 1;77(9):2306-2317. https://aacrjournals.org/cancerres/article/77/9/2306/625038/MYC-Mediates-Large-Oncosome-Induced-Fibroblast Conley A, Minciacchi VR, Lee DH, Knudsen BS, Karlan BY, Citrigno L, Viglietto G, Tewari M, Freeman MR, Demichelis F, Di Vizio D.
2017 Sep;20(3):251–258. https://www.nature.com/articles/pcan20177. Minciacchi VR, Spinelli C, Reis-Sobreiro M, Cavallini L, You S, Zandian M, Li X, Chiarugi P, Adam RM, Posadas EM, Viglietto G, Freeman MR, Cocucci E, Bhowmick NA, Di Vizio D. MYC mediates large oncosome-induced fibroblast reprogramming in prostate cancer. Cancer Res. 2017 May 1;77(9):2306-2317. https://aacrjournals.org/cancerres/article/77/9/2306/625038/MYC-Mediates-Large-Oncosome-Induced-Fibroblast Conley A, Minciacchi VR, Lee DH, Knudsen BS, Karlan BY, Citrigno L, Viglietto G, Tewari M, Freeman MR, Demichelis F, Di Vizio D.
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Harper Kim 2 minutes ago
High-throughput sequencing of two populations of extracellular vesicles provides an mRNA signature t...
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Minciacchi VR, You S, Spinelli C, Morley S, Zandian M, Aspuria P, Cavallini L, Ciardiello C, Reis So...
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High-throughput sequencing of two populations of extracellular vesicles provides an mRNA signature that can be detected in the circulation of breast cancer patients. RNA Biol. 2017 Mar 4;14(3):305-316. https://www.tandfonline.com/doi/full/10.1080/15476286.2016.1259061. Minciacchi VR, Freeman MR, Di Vizio D. Extracellular vesicles in cancer: exosomes, microvesicles and the emerging role of large oncosomes. Semin Cell Dev Biol. 2015 Apr;40:41-51. https://www.sciencedirect.com/science/article/pii/S1084952115000373.
High-throughput sequencing of two populations of extracellular vesicles provides an mRNA signature that can be detected in the circulation of breast cancer patients. RNA Biol. 2017 Mar 4;14(3):305-316. https://www.tandfonline.com/doi/full/10.1080/15476286.2016.1259061. Minciacchi VR, Freeman MR, Di Vizio D. Extracellular vesicles in cancer: exosomes, microvesicles and the emerging role of large oncosomes. Semin Cell Dev Biol. 2015 Apr;40:41-51. https://www.sciencedirect.com/science/article/pii/S1084952115000373.
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Minciacchi VR, You S, Spinelli C, Morley S, Zandian M, Aspuria P, Cavallini L, Ciardiello C, Reis Sobreiro M, Morello M, Kharmate G, Jang SC, Kim DK, Hosseini-Beheshti E, Tomlinson Guns E, Gleave M, Gho YS, Mathivanan S, Yang W, Freeman MR, Di Vizio D. Large oncosomes contain distinct protein cargo and represent a separate functional class of tumor-derived extracellular vesicles. Oncotarget. 2015 May 10;6(13):11327–11341. http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=3598. Kim OY, Choi SJ, Jang SC, Park KS, Kim SR, Choi JP, Lim JH, Lee SW, Park J, Di Vizio D, et al.
Minciacchi VR, You S, Spinelli C, Morley S, Zandian M, Aspuria P, Cavallini L, Ciardiello C, Reis Sobreiro M, Morello M, Kharmate G, Jang SC, Kim DK, Hosseini-Beheshti E, Tomlinson Guns E, Gleave M, Gho YS, Mathivanan S, Yang W, Freeman MR, Di Vizio D. Large oncosomes contain distinct protein cargo and represent a separate functional class of tumor-derived extracellular vesicles. Oncotarget. 2015 May 10;6(13):11327–11341. http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=3598. Kim OY, Choi SJ, Jang SC, Park KS, Kim SR, Choi JP, Lim JH, Lee SW, Park J, Di Vizio D, et al.
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Bacterial protoplast-derived nanovesicles as vaccine delivery system against bacterial infection. N...
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Morello M, Minciacchi VR, de Candia P, Yang J, Posadas E, Kim H, Griffiths D, Bhowmick N, Chung LW, ...
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Bacterial protoplast-derived nanovesicles as vaccine delivery system against bacterial infection. Nano Lett. 2015 Jan 14;15(1):266-274. https://pubs.acs.org/doi/10.1021/nl503508h.
Bacterial protoplast-derived nanovesicles as vaccine delivery system against bacterial infection. Nano Lett. 2015 Jan 14;15(1):266-274. https://pubs.acs.org/doi/10.1021/nl503508h.
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Oliver Taylor 10 minutes ago
Morello M, Minciacchi VR, de Candia P, Yang J, Posadas E, Kim H, Griffiths D, Bhowmick N, Chung LW, ...
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Hannah Kim 7 minutes ago
Ayala G, Morello M, Frolov A, You S, Li R, Rosati F, Bartolucci G, Danza G, Adam RM, Thompson TC, Li...
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Morello M, Minciacchi VR, de Candia P, Yang J, Posadas E, Kim H, Griffiths D, Bhowmick N, Chung LW, Gandellini P, Freeman MR, Demichelis F, Di Vizio D. Large oncosomes mediate intercellular transfer of functional microRNA. Cell Cycle. 2013 Nov 15;12(22):3526-3536. https://www.tandfonline.com/doi/abs/10.4161/cc.26539. Israelsen WJ, Dayton TL, Davidson SM, Fiske BP, Hosios AM, Bellinger G, Li J, Yu Y, Sasaki M, Horner JW, Burga LN, Xie J, Jurczak MJ, DePinho RA, Clish CB, Jacks T, Kibbey RG, Wulf GM, Di Vizio D, et al. PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells. Cell. 2013 Oct 10;155(2):397-409. https://www.cell.com/cell/fulltext/S0092-8674(13)01162-8.
Morello M, Minciacchi VR, de Candia P, Yang J, Posadas E, Kim H, Griffiths D, Bhowmick N, Chung LW, Gandellini P, Freeman MR, Demichelis F, Di Vizio D. Large oncosomes mediate intercellular transfer of functional microRNA. Cell Cycle. 2013 Nov 15;12(22):3526-3536. https://www.tandfonline.com/doi/abs/10.4161/cc.26539. Israelsen WJ, Dayton TL, Davidson SM, Fiske BP, Hosios AM, Bellinger G, Li J, Yu Y, Sasaki M, Horner JW, Burga LN, Xie J, Jurczak MJ, DePinho RA, Clish CB, Jacks T, Kibbey RG, Wulf GM, Di Vizio D, et al. PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells. Cell. 2013 Oct 10;155(2):397-409. https://www.cell.com/cell/fulltext/S0092-8674(13)01162-8.
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Ayala G, Morello M, Frolov A, You S, Li R, Rosati F, Bartolucci G, Danza G, Adam RM, Thompson TC, Li...
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Zoe Mueller 5 minutes ago
Large oncosomes in human prostate cancer tissues and in the circulation of mice with metastatic dise...
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Ayala G, Morello M, Frolov A, You S, Li R, Rosati F, Bartolucci G, Danza G, Adam RM, Thompson TC, Lisanti MP, Freeman MR, Di Vizio D. Loss of caveolin-1 in prostate cancer stroma correlates with reduced relapse-free survival and is functionally relevant to tumour progression. J Pathol. 2013 Sep;231(1):77-87. https://onlinelibrary.wiley.com/doi/abs/10.1002/path.4217. Di Vizio D, Morello M, Dudley AC, Schow PW, Adam RM, Morley S, Mulholland D, Rotinen M, Hager MH, Insabato L, et al.
Ayala G, Morello M, Frolov A, You S, Li R, Rosati F, Bartolucci G, Danza G, Adam RM, Thompson TC, Lisanti MP, Freeman MR, Di Vizio D. Loss of caveolin-1 in prostate cancer stroma correlates with reduced relapse-free survival and is functionally relevant to tumour progression. J Pathol. 2013 Sep;231(1):77-87. https://onlinelibrary.wiley.com/doi/abs/10.1002/path.4217. Di Vizio D, Morello M, Dudley AC, Schow PW, Adam RM, Morley S, Mulholland D, Rotinen M, Hager MH, Insabato L, et al.
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Large oncosomes in human prostate cancer tissues and in the circulation of mice with metastatic dise...
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Large oncosomes in human prostate cancer tissues and in the circulation of mice with metastatic disease. Am J Pathol. 2012 Nov;181(5):1573-1584. https://ajp.amjpathol.org/article/S0002-9440(12)00600-1/fulltext. Di Vizio D, Kim J, Hager MH, Morello M, Yang W, Lafargue CJ, True LD, Rubin MA, Adam RM, Beroukhim R, et al.
Large oncosomes in human prostate cancer tissues and in the circulation of mice with metastatic disease. Am J Pathol. 2012 Nov;181(5):1573-1584. https://ajp.amjpathol.org/article/S0002-9440(12)00600-1/fulltext. Di Vizio D, Kim J, Hager MH, Morello M, Yang W, Lafargue CJ, True LD, Rubin MA, Adam RM, Beroukhim R, et al.
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Oncosome formation in prostate cancer: association with a region of frequent chromosomal deletion in metastatic disease. Cancer Res. 2009 Jul 1;69(13):5601-5609. https://aacrjournals.org/cancerres/article/69/13/5601/549842/Oncosome-Formation-in-Prostate-Cancer-Association 
  Contact the Di Vizio Lab 8700 Beverly Blvd. Davis Building, Room 5094A Los Angeles, CA 90048 
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Oncosome formation in prostate cancer: association with a region of frequent chromosomal deletion in metastatic disease. Cancer Res. 2009 Jul 1;69(13):5601-5609. https://aacrjournals.org/cancerres/article/69/13/5601/549842/Oncosome-Formation-in-Prostate-Cancer-Association Contact the Di Vizio Lab 8700 Beverly Blvd. Davis Building, Room 5094A Los Angeles, CA 90048 Lab 310-423-7383 Office 310-967-0622 Send a Message Please ensure Javascript is enabled for purposes of website accessibility
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