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% How Does Cancer Spread in Blood? Cedars-Sinai Skip to main content Close Select your preferred language English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog Menu Close Call 1-800-CEDARS-1 toggle search form Close Los Angeles, 09 July 2020 06:00 AM America/Los_Angeles Study Sheds Light on How Cancer Spreads in Blood Analysis of Particles Shed by Tumors Points to New Less Invasive Way to Diagnose Malignancies Extracellular vesicles. Image courtesy of the National Institutes of Health.
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% How Does Cancer Spread in Blood? Cedars-Sinai Skip to main content Close Select your preferred language English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog Menu Close Call 1-800-CEDARS-1 toggle search form Close Los Angeles, 09 July 2020 06:00 AM America/Los_Angeles Study Sheds Light on How Cancer Spreads in Blood Analysis of Particles Shed by Tumors Points to New Less Invasive Way to Diagnose Malignancies Extracellular vesicles. Image courtesy of the National Institutes of Health.
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Joseph Kim 2 minutes ago
A new study sheds light on proteins in particles called extracellular vesicles, which are released b...
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Thomas Anderson 1 minutes ago
The research is a large-scale analysis of what are known as palmitoylated proteins inside extracellu...
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A new study sheds light on proteins in particles called extracellular vesicles, which are released by tumor cells into the bloodstream and promote the spread of cancer. The findings suggest how a blood test involving these vesicles might be used to diagnose cancer in the future, avoiding the need for invasive surgical biopsies.
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A new study sheds light on proteins in particles called extracellular vesicles, which are released by tumor cells into the bloodstream and promote the spread of cancer. The findings suggest how a blood test involving these vesicles might be used to diagnose cancer in the future, avoiding the need for invasive surgical biopsies.
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Sophie Martin 2 minutes ago
The research is a large-scale analysis of what are known as palmitoylated proteins inside extracellu...
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Zoe Mueller 2 minutes ago
Extracellular vesicles have gained significant attention in the last decade because they contain pro...
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The research is a large-scale analysis of what are known as palmitoylated proteins inside extracellular vesicles, according to Dolores Di Vizio, MD, PhD, professor of Surgery, Biomedical Sciences and Pathology and Laboratory Medicine at Cedars-Sinai. Di Vizio is co-corresponding author of the study, published online June 10 in the Journal of Extracellular Vesicles.
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The research is a large-scale analysis of what are known as palmitoylated proteins inside extracellular vesicles, according to Dolores Di Vizio, MD, PhD, professor of Surgery, Biomedical Sciences and Pathology and Laboratory Medicine at Cedars-Sinai. Di Vizio is co-corresponding author of the study, published online June 10 in the Journal of Extracellular Vesicles.
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Sophia Chen 6 minutes ago
Extracellular vesicles have gained significant attention in the last decade because they contain pro...
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Zoe Mueller 9 minutes ago
To learn more about this process, the research team looked into a process called palmitoylation, in ...
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Extracellular vesicles have gained significant attention in the last decade because they contain proteins and other biologically important molecules whose information can be transferred from cell to cell. They are known to help cancer metastasize to distant sites in the body, but exactly how this happens is not clear.
Kevin Wang Member
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Extracellular vesicles have gained significant attention in the last decade because they contain proteins and other biologically important molecules whose information can be transferred from cell to cell. They are known to help cancer metastasize to distant sites in the body, but exactly how this happens is not clear.
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Andrew Wilson 16 minutes ago
To learn more about this process, the research team looked into a process called palmitoylation, in ...
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To learn more about this process, the research team looked into a process called palmitoylation, in which enzymes transfer lipid molecules onto proteins. Palmitoylation can affect where proteins are located within cells, their activities and their contribution to cancer progression.
Daniel Kumar Member
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To learn more about this process, the research team looked into a process called palmitoylation, in which enzymes transfer lipid molecules onto proteins. Palmitoylation can affect where proteins are located within cells, their activities and their contribution to cancer progression.
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Lily Watson 14 minutes ago
The investigators examined two types of extracellular vesicles, small and large, in samples of human...
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Further, when the team chemically suppressed the palmitoylation process, the level of some of these ...
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The investigators examined two types of extracellular vesicles, small and large, in samples of human prostate cancer cells. Using centrifuges, they separated the extracellular vesicles from the other cell materials and analyzed the levels of palmitoylation and the types of proteins present. The team found extracellular vesicles derived from the cancer cells contained palmitoylated proteins that are associated with the spread of cancer.
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The investigators examined two types of extracellular vesicles, small and large, in samples of human prostate cancer cells. Using centrifuges, they separated the extracellular vesicles from the other cell materials and analyzed the levels of palmitoylation and the types of proteins present. The team found extracellular vesicles derived from the cancer cells contained palmitoylated proteins that are associated with the spread of cancer.
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Lucas Martinez 3 minutes ago
Further, when the team chemically suppressed the palmitoylation process, the level of some of these ...
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"This finding raises the possibility that by examining these proteins in extracellular vesi...
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Further, when the team chemically suppressed the palmitoylation process, the level of some of these proteins went down in the extracellular vesicles. "Our results suggest that protein palmitoylation may be involved in the selective packaging of proteins to different extracellular vesicle populations in the body," Di Vizio said.
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Further, when the team chemically suppressed the palmitoylation process, the level of some of these proteins went down in the extracellular vesicles. "Our results suggest that protein palmitoylation may be involved in the selective packaging of proteins to different extracellular vesicle populations in the body," Di Vizio said.
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"This finding raises the possibility that by examining these proteins in extracellular vesi...
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Javier Mariscal, PhD, a postdoctoral scientist in Di Vizio's laboratory, is the study&#3...
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"This finding raises the possibility that by examining these proteins in extracellular vesicles in the bloodstream, we may be able to detect and characterize cancer in a patient in the future without performing a surgical biopsy." Di Vizio said the next step in the research is to conduct a study in collaboration with her Cedars-Sinai colleagues and industry partners that will use advanced technologies, including mass spectrometry and flow cytometry, with the goal of identifying clinically significant prostate cancer at diagnosis.  In addition to Di Vizio, Wei Yang, PhD, associate professor of Surgery at Cedars-Sinai, and Andries Zijlstra, PhD, are co-corresponding authors for the study. Zijlstra completed the research while working at Vanderbilt University Medical Center in Nashville.
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"This finding raises the possibility that by examining these proteins in extracellular vesicles in the bloodstream, we may be able to detect and characterize cancer in a patient in the future without performing a surgical biopsy." Di Vizio said the next step in the research is to conduct a study in collaboration with her Cedars-Sinai colleagues and industry partners that will use advanced technologies, including mass spectrometry and flow cytometry, with the goal of identifying clinically significant prostate cancer at diagnosis.  In addition to Di Vizio, Wei Yang, PhD, associate professor of Surgery at Cedars-Sinai, and Andries Zijlstra, PhD, are co-corresponding authors for the study. Zijlstra completed the research while working at Vanderbilt University Medical Center in Nashville.
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Javier Mariscal, PhD, a postdoctoral scientist in Di Vizio's laboratory, is the study's first author. Funding: Research reported in this publication was supported by the National Institutes of Health under award number R01CA218526 and by the U.S. Department of Defense.
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Javier Mariscal, PhD, a postdoctoral scientist in Di Vizio's laboratory, is the study's first author. Funding: Research reported in this publication was supported by the National Institutes of Health under award number R01CA218526 and by the U.S. Department of Defense.
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DOI: 10.1080/20013078.2020.1764192 Read more in the Cedars-Sinai Blog: Could Walnuts Prove Beneficial for Prostate Cancer Patients? Related Stories RSS feed - Related Stories (opens in new window) View all headlines - Related Stories Cedars-Sinai Schedules Free Flu Vaccine Clinics October 05, 2022 06:13 AM America/Los_Angeles Cedars-Sinai is opening free flu vaccine pop-up clinics to help the community combat the upcoming flu season, which is shaping up to be a rough one.“We want to make it as easy as possible for people … Read more Cedars-Sinai Showcases Hispanic and Latinx Art October 04, 2022 06:05 AM America/Los_Angeles Cedars-Sinai is celebrating Hispanic and Latinx Heritage Month with a specially curated gallery showcasing the work of Hispanic and Latinx artists.The artwork is available to the public through a … Read more 15 Years of Heart October 03, 2022 06:01 AM America/Los_Angeles Pioneering heart care is a tradition at Cedars-Sinai.
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DOI: 10.1080/20013078.2020.1764192 Read more in the Cedars-Sinai Blog: Could Walnuts Prove Beneficial for Prostate Cancer Patients? Related Stories RSS feed - Related Stories (opens in new window) View all headlines - Related Stories Cedars-Sinai Schedules Free Flu Vaccine Clinics October 05, 2022 06:13 AM America/Los_Angeles Cedars-Sinai is opening free flu vaccine pop-up clinics to help the community combat the upcoming flu season, which is shaping up to be a rough one.“We want to make it as easy as possible for people … Read more Cedars-Sinai Showcases Hispanic and Latinx Art October 04, 2022 06:05 AM America/Los_Angeles Cedars-Sinai is celebrating Hispanic and Latinx Heritage Month with a specially curated gallery showcasing the work of Hispanic and Latinx artists.The artwork is available to the public through a … Read more 15 Years of Heart October 03, 2022 06:01 AM America/Los_Angeles Pioneering heart care is a tradition at Cedars-Sinai.
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It’s a tradition that took root in 1924, when Cedars-Sinai became home to the first electrocardiogram machine in Los Angeles. The roots grew … Read more Show previous items Show next items Contact the Media Team Email: newsroom@cshs.org Share this release Study Sheds Light on How Cancer Spreads in Blood Share on: Twitter Share on: Facebook Share on: LinkedIn Search Our Newsroom Social media Visit our Facebook page (opens in new window) Follow us on Twitter (opens in new window) Visit our Youtube profile (opens in new window) (opens in new window) Latest news 07 Oct 2022 - HealthDay: Black Women Less Likely to Get Laparoscopic Fibroid Surgeries 07 Oct 2022 - Faculty Publications: Sept. 29-Oct.
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It’s a tradition that took root in 1924, when Cedars-Sinai became home to the first electrocardiogram machine in Los Angeles. The roots grew … Read more Show previous items Show next items Contact the Media Team Email: [email protected] Share this release Study Sheds Light on How Cancer Spreads in Blood Share on: Twitter Share on: Facebook Share on: LinkedIn Search Our Newsroom Social media Visit our Facebook page (opens in new window) Follow us on Twitter (opens in new window) Visit our Youtube profile (opens in new window) (opens in new window) Latest news 07 Oct 2022 - HealthDay: Black Women Less Likely to Get Laparoscopic Fibroid Surgeries 07 Oct 2022 - Faculty Publications: Sept. 29-Oct.
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