% Xiaflex and Cost: Financial Assistance Options, Savings, More Health ConditionsFeaturedBreast CancerIBD MigraineMultiple Sclerosis (MS)Rheumatoid ArthritisType 2 DiabetesSponsored TopicsArticlesAcid RefluxADHDAllergiesAlzheimer's & DementiaBipolar DisorderCancerCrohn's DiseaseChronic PainCold & FluCOPDDepressionFibromyalgiaHeart DiseaseHigh CholesterolHIVHypertensionIPFOsteoarthritisPsoriasisSkin Disorders and CareSTDsDiscoverWellness TopicsNutritionFitnessSkin CareSexual HealthWomen's HealthMental HealthSleepOriginal SeriesFresh Food FastDiagnosis DiariesYou’re Not AlonePresent TenseVideo SeriesYouth in FocusHealthy HarvestNo More SilenceFuture of HealthPlanHealth ChallengesMindful EatingSugar SavvyMove Your BodyGut HealthMood FoodsAlign Your SpineFind CarePrimary CareMental HealthOB-GYNDermatologistsNeurologistsCardiologistsOrthopedistsLifestyle QuizzesWeight ManagementAm I Depressed? A Quiz for TeensAre You a Workaholic?How Well Do You Sleep?Tools & ResourcesHealth NewsFind a DietFind Healthy SnacksDrugs A-ZHealth A-ZConnectFind Your Bezzy CommunityBreast CancerInflammatory Bowel DiseasePsoriatic ArthritisMigraineMultiple SclerosisPsoriasisFollow us on social mediaShopProducts by ConditionInsomniaStress ReliefBack PainNeck PainSleep ApneaHot SleepersAllergiesPain ReliefProduct ReviewsVitamins & SupplementsSleepMental HealthNutritionAt-Home TestingCBDMen’s HealthWomen’s HealthHealth ConditionsDiscoverPlanConnectShopSubscribe
Xiaflex and Cost What You Need to Know
Medically reviewed by Damilola Omopariola, PharmD, BCACP — By Jen Seabright, PharmD on October 19, 2022
Introduction
If you’re looking at treatment options for Dupuytren’s contracture or Peyronie’s disease, you may want to learn more about Xiaflex (collagenase clostridium histolyticum). It’s a prescription drug that’s used to treat these two conditions in adults.
thumb_upLike (32)
commentReply (2)
shareShare
visibility987 views
thumb_up32 likes
comment
2 replies
C
Charlotte Lee 4 minutes ago
Dupuytren’s contracture is a condition that causes a buildup of connective tissue in your hands. T...
A
Amelia Singh 1 minutes ago
With Peyronie’s disease, plaques (scar tissue) form in the penis, which can cause the penis to cur...
T
Thomas Anderson Member
access_time
6 minutes ago
Wednesday, 07 May 2025
Dupuytren’s contracture is a condition that causes a buildup of connective tissue in your hands. This may lead to being unable to straighten one or more fingers.
thumb_upLike (27)
commentReply (2)
thumb_up27 likes
comment
2 replies
J
Julia Zhang 6 minutes ago
With Peyronie’s disease, plaques (scar tissue) form in the penis, which can cause the penis to cur...
S
Scarlett Brown 2 minutes ago
They’ll then give the mixture as an injection into the affected area. Keep reading for details on ...
J
Jack Thompson Member
access_time
15 minutes ago
Wednesday, 07 May 2025
With Peyronie’s disease, plaques (scar tissue) form in the penis, which can cause the penis to curve painfully when erect. Xiaflex comes as a powder that a healthcare professional mixes with liquid.
thumb_upLike (36)
commentReply (2)
thumb_up36 likes
comment
2 replies
S
Sophia Chen 8 minutes ago
They’ll then give the mixture as an injection into the affected area. Keep reading for details on ...
N
Nathan Chen 12 minutes ago
Note: For more details on Xiaflex, see this in-depth article.
How much do Xiaflex injections cos...
N
Noah Davis Member
access_time
12 minutes ago
Wednesday, 07 May 2025
They’ll then give the mixture as an injection into the affected area. Keep reading for details on Xiaflex and cost, and how to save money on prescriptions.
thumb_upLike (1)
commentReply (3)
thumb_up1 likes
comment
3 replies
C
Christopher Lee 9 minutes ago
Note: For more details on Xiaflex, see this in-depth article.
How much do Xiaflex injections cos...
M
Madison Singh 3 minutes ago
It will also depend on how much you have to pay for an office visit with a healthcare professional t...
Note: For more details on Xiaflex, see this in-depth article.
How much do Xiaflex injections cost
The price you pay for Xiaflex can vary. Your cost may depend on your treatment plan, your insurance coverage (if you have it), and the pharmacy you use.
thumb_upLike (49)
commentReply (3)
thumb_up49 likes
comment
3 replies
E
Ethan Thomas 14 minutes ago
It will also depend on how much you have to pay for an office visit with a healthcare professional t...
Z
Zoe Mueller 1 minutes ago
Note: If you have insurance, you may need to get prior authorization before your insurance provider ...
It will also depend on how much you have to pay for an office visit with a healthcare professional to receive Xiaflex. You’ll likely need follow-up appointments so your doctor can check how well the drug is working for you. To find out how much you’ll pay for Xiaflex, talk with your doctor or insurance provider.
thumb_upLike (24)
commentReply (2)
thumb_up24 likes
comment
2 replies
D
Dylan Patel 7 minutes ago
Note: If you have insurance, you may need to get prior authorization before your insurance provider ...
A
Alexander Wang 9 minutes ago
If Xiaflex requires prior authorization and you don’t receive it before you start treatment, you c...
D
Dylan Patel Member
access_time
21 minutes ago
Wednesday, 07 May 2025
Note: If you have insurance, you may need to get prior authorization before your insurance provider will cover Xiaflex. This means your insurer and your doctor will discuss Xiaflex in regard to your treatment. Then the insurance company will determine whether the drug is covered.
thumb_upLike (16)
commentReply (3)
thumb_up16 likes
comment
3 replies
A
Alexander Wang 16 minutes ago
If Xiaflex requires prior authorization and you don’t receive it before you start treatment, you c...
M
Madison Singh 21 minutes ago
FAQs about cost and Xiaflex
Below are answers to some frequently asked questions about Xiaf...
If Xiaflex requires prior authorization and you don’t receive it before you start treatment, you could pay the full cost of the drug. Be sure to ask your insurance company whether Xiaflex requires prior authorization.
thumb_upLike (13)
commentReply (1)
thumb_up13 likes
comment
1 replies
C
Chloe Santos 16 minutes ago
FAQs about cost and Xiaflex
Below are answers to some frequently asked questions about Xiaf...
E
Evelyn Zhang Member
access_time
18 minutes ago
Wednesday, 07 May 2025
FAQs about cost and Xiaflex
Below are answers to some frequently asked questions about Xiaflex and cost.
What is the price of Xiaflex with Medicare coverage
The price of Xiaflex you’ll pay depends on your specific Medicare plan.
thumb_upLike (36)
commentReply (2)
thumb_up36 likes
comment
2 replies
N
Natalie Lopez 17 minutes ago
You may pay a different amount depending on whether you have a Medicare Advantage plan or Medicare P...
I
Isaac Schmidt 5 minutes ago
Either can let you know what you’ll pay for Xiaflex.
How much is the cost per injection of Xia...
D
Daniel Kumar Member
access_time
30 minutes ago
Wednesday, 07 May 2025
You may pay a different amount depending on whether you have a Medicare Advantage plan or Medicare Part B. Some Medicare plans may not cover Xiaflex. If you have a Medicare plan, contact your doctor or your Medicare plan provider.
thumb_upLike (15)
commentReply (1)
thumb_up15 likes
comment
1 replies
D
Dylan Patel 27 minutes ago
Either can let you know what you’ll pay for Xiaflex.
How much is the cost per injection of Xia...
D
David Cohen Member
access_time
55 minutes ago
Wednesday, 07 May 2025
Either can let you know what you’ll pay for Xiaflex.
How much is the cost per injection of Xiaflex with insurance and without insurance
The amount you pay for an injection of Xiaflex depends on several factors, not just whether you have insurance coverage. But if you don’t have insurance, you’ll likely pay more for the drug.
thumb_upLike (0)
commentReply (3)
thumb_up0 likes
comment
3 replies
I
Isaac Schmidt 7 minutes ago
The drugmaker of Xiaflex has a copay assistance program that might help cover the cost of Xiaflex. (...
E
Ethan Thomas 25 minutes ago
But if you have government insurance such as Medicare, you won’t qualify for this program. For a f...
The drugmaker of Xiaflex has a copay assistance program that might help cover the cost of Xiaflex. (A copay is a fixed amount that your insurance plan might require you to pay for your medication.) You may be eligible for this program even if you don’t have insurance.
thumb_upLike (42)
commentReply (0)
thumb_up42 likes
A
Alexander Wang Member
access_time
52 minutes ago
Wednesday, 07 May 2025
But if you have government insurance such as Medicare, you won’t qualify for this program. For a few other resources that may help you pay less for Xiaflex with or without insurance, see the “Can I get help paying for Xiaflex ” section below.
thumb_upLike (14)
commentReply (3)
thumb_up14 likes
comment
3 replies
L
Liam Wilson 24 minutes ago
Your doctor may also have suggestions for ways to save on the cost of this drug.
Does the cost o...
R
Ryan Garcia 12 minutes ago
If you have insurance, your insurance company determines what medications and conditions it will cov...
If you have insurance, your insurance company determines what medications and conditions it will cover. It also determines what copays or other costs you may have to pay. Also, the number of Xiaflex injections you receive may depend on the severity of your Dupuytren’s contracture or Peyronie’s disease.
thumb_upLike (10)
commentReply (1)
thumb_up10 likes
comment
1 replies
S
Sophia Chen 40 minutes ago
And you’ll likely need to visit your doctor after each injection so they can see how well the drug...
C
Chloe Santos Moderator
access_time
80 minutes ago
Wednesday, 07 May 2025
And you’ll likely need to visit your doctor after each injection so they can see how well the drug is working for you.
Can I get help paying for Xiaflex
If you need help covering the cost of Xiaflex or understanding your insurance, check out these resources:Xiaflex Copay Assistance ProgramNeedyMedsMedicine Assistance Tool
On these sites, you can find insurance information, details on drug assistance programs, and other services. If you have questions about how to pay for your prescription, talk with your doctor or pharmacist.
thumb_upLike (9)
commentReply (2)
thumb_up9 likes
comment
2 replies
A
Aria Nguyen 29 minutes ago
Is Xiaflex available as a generic or biosimilar
Xiaflex only comes as a brand-name medicat...
D
Dylan Patel 75 minutes ago
Biosimilars are like generic drugs. Unlike generics, which are made for nonbiologic drugs, biosimila...
S
Sophia Chen Member
access_time
51 minutes ago
Wednesday, 07 May 2025
Is Xiaflex available as a generic or biosimilar
Xiaflex only comes as a brand-name medication. Xiaflex is a biologic drug, which means it’s made from parts of living organisms. It doesn’t come in a biosimilar form.
thumb_upLike (33)
commentReply (0)
thumb_up33 likes
A
Audrey Mueller Member
access_time
90 minutes ago
Wednesday, 07 May 2025
Biosimilars are like generic drugs. Unlike generics, which are made for nonbiologic drugs, biosimilars are made for biologic drugs.Why is there such a cost difference between biologic drugs and biosimilar drugs?
thumb_upLike (13)
commentReply (2)
thumb_up13 likes
comment
2 replies
N
Natalie Lopez 3 minutes ago
Biologic drugs can be expensive because of the research and testing needed to ensure their safety an...
O
Oliver Taylor 8 minutes ago
This competition in the market may lead to lower costs for biosimilars. And because biosimilars are ...
A
Amelia Singh Moderator
access_time
38 minutes ago
Wednesday, 07 May 2025
Biologic drugs can be expensive because of the research and testing needed to ensure their safety and effectiveness. The drugmaker of a biologic drug can sell it for up to 12 years. When the biologic drug’s patent expires, other drugmakers can create biosimilar versions.
thumb_upLike (34)
commentReply (3)
thumb_up34 likes
comment
3 replies
N
Nathan Chen 20 minutes ago
This competition in the market may lead to lower costs for biosimilars. And because biosimilars are ...
S
Scarlett Brown 3 minutes ago
This can also lead to lower costs for biosimilars.
This competition in the market may lead to lower costs for biosimilars. And because biosimilars are very similar to biologic drugs, they don’t need to be studied again.
thumb_upLike (49)
commentReply (3)
thumb_up49 likes
comment
3 replies
L
Luna Park 17 minutes ago
This can also lead to lower costs for biosimilars.
What should my next steps be
If you sti...
Z
Zoe Mueller 45 minutes ago
They may be able to give you a better idea of what you’ll pay for this drug. But if you have healt...
This can also lead to lower costs for biosimilars.
What should my next steps be
If you still have questions about the cost of Xiaflex, talk with your doctor or pharmacist.
thumb_upLike (9)
commentReply (0)
thumb_up9 likes
A
Audrey Mueller Member
access_time
110 minutes ago
Wednesday, 07 May 2025
They may be able to give you a better idea of what you’ll pay for this drug. But if you have health insurance, you’ll need to talk to your insurance provider to learn the actual cost you’d pay for Xiaflex.
thumb_upLike (40)
commentReply (0)
thumb_up40 likes
I
Isaac Schmidt Member
access_time
115 minutes ago
Wednesday, 07 May 2025
Examples of questions you may want to ask your doctor or insurance provider include:Are there other lower-cost drugs that could treat my condition?Are there other treatment options if I can’t afford Xiaflex?What savings programs may I qualify for that apply to my Xiaflex prescription? To learn more about Xiaflex, see these articles:All About XiaflexSide Effects of Xiaflex: What You Need to KnowDosage Details for Xiaflex
To get information on different conditions and tips for improving your health, subscribe to any of Healthline’s newsletters. You may also want to check out the online communities at Bezzy.
thumb_upLike (24)
commentReply (2)
thumb_up24 likes
comment
2 replies
L
Luna Park 96 minutes ago
It’s a place where people with certain conditions can find support and connect with others. Discla...
B
Brandon Kumar 35 minutes ago
However, this article should not be used as a substitute for the knowledge and expertise of a licens...
J
Joseph Kim Member
access_time
120 minutes ago
Wednesday, 07 May 2025
It’s a place where people with certain conditions can find support and connect with others. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date.
thumb_upLike (24)
commentReply (3)
thumb_up24 likes
comment
3 replies
A
Andrew Wilson 26 minutes ago
However, this article should not be used as a substitute for the knowledge and expertise of a licens...
H
Hannah Kim 47 minutes ago
The absence of warnings or other information for a given drug does not indicate that the drug or dru...
However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects.
thumb_upLike (13)
commentReply (1)
thumb_up13 likes
comment
1 replies
J
Joseph Kim 113 minutes ago
The absence of warnings or other information for a given drug does not indicate that the drug or dru...
D
Daniel Kumar Member
access_time
78 minutes ago
Wednesday, 07 May 2025
The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Last medically reviewed on October 19, 2022
How we vetted this article
SourcesHistoryHealthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references.
thumb_upLike (0)
commentReply (0)
thumb_up0 likes
M
Mason Rodriguez Member
access_time
135 minutes ago
Wednesday, 07 May 2025
You can learn more about how we ensure our content is accurate and current by reading our editorial policy.Xiaflex (collagenase clostridium histolyticum) for injection, for intralesional use. (8/2022). accessdata.fda.gov/drugsatfda_docs/label/2022/125338s129lbl.pdfDrugs@FDA: FDA-approved drugs. (n.d.). accessdata.fda.gov/scripts/cder/daf/Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available.
thumb_upLike (8)
commentReply (2)
thumb_up8 likes
comment
2 replies
I
Isabella Johnson 71 minutes ago
Current Version
Oct 19, 2022
By
Jen Seabright, PharmD
Edited By
Nizam Khan (TechSpace)
Medically Rev...
J
James Smith 101 minutes ago
Here are some ways you can get relief from discomfort and other symptoms.READ MOREEverything You Nee...
E
Ella Rodriguez Member
access_time
28 minutes ago
Wednesday, 07 May 2025
Current Version
Oct 19, 2022
By
Jen Seabright, PharmD
Edited By
Nizam Khan (TechSpace)
Medically Reviewed By
Damilola Omopariola, PharmD, BCACP
Share this articleMedically reviewed by Damilola Omopariola, PharmD, BCACP — By Jen Seabright, PharmD on October 19, 2022
related stories
8 Pain Relief Tips for Dupuytren’s ContractureEverything You Need to Know About Penis HealthLedderhose DiseasePossible Causes of Penis Pain and How to Treat ItWhat Causes Penis Shrinkage?
Read this next
8 Pain Relief Tips for Dupuytren’s ContractureMedically reviewed by Angela M. Bell, MD, FACP
Dupuytren's contracture can cause pain, itching, and mobility issues.
thumb_upLike (28)
commentReply (2)
thumb_up28 likes
comment
2 replies
N
Noah Davis 6 minutes ago
Here are some ways you can get relief from discomfort and other symptoms.READ MOREEverything You Nee...
R
Ryan Garcia 12 minutes ago
It may be the result of an accident…READ MOREWhat Causes Penis Shrinkage?Medically reviewed by Ala...
N
Natalie Lopez Member
access_time
145 minutes ago
Wednesday, 07 May 2025
Here are some ways you can get relief from discomfort and other symptoms.READ MOREEverything You Need to Know About Penis HealthMedically reviewed by Stacy Sampson, D.O. When most people think about penis health, they think about sexually transmitted infections and erectile dysfunction. While these conditions can…READ MORELedderhose DiseaseMedically reviewed by Gregory Minnis, DPT
Learn about Ledderhose disease, including different treatment options such as surgery.READ MOREPossible Causes of Penis Pain and How to Treat ItMedically reviewed by Alana Biggers, M.D., MPH
Penile pain is an itching, burning, or throbbing sensation in the base, shaft, head, or foreskin of your penis.
thumb_upLike (39)
commentReply (3)
thumb_up39 likes
comment
3 replies
M
Mason Rodriguez 25 minutes ago
It may be the result of an accident…READ MOREWhat Causes Penis Shrinkage?Medically reviewed by Ala...
E
Evelyn Zhang 11 minutes ago
Learn about Teva sildenafil and how…READ MOREHydrocele: Causes, Symptoms, and TreatmentMedically r...
It may be the result of an accident…READ MOREWhat Causes Penis Shrinkage?Medically reviewed by Alana Biggers, M.D., MPH
Learn possible causes for penis shrinkage and how to manage this symptom.READ MORE6 Best At-Home Testosterone Test Kits of 2022 and What You Need to Know About ThemMedically reviewed by Matt Coward, MD, FACS
Before you try a home testosterone test kit, make sure you understand how it works, how reliable it is, what information you'll get, and what to do…READ MOREPenile MelanosisMedically reviewed by Alana Biggers, M.D., MPH
Penile melanosis is characterized by small patches of dark skin on the penis. We’ll explain possible causes and treatment options.READ MOREWhat to Expect from a Penile ImplantMedically reviewed by Matt Coward, MD, FACS
Learn what to expect from penile implant surgery.READ MORETeva Sildenafil: Generic Viagra, Pros and Cons, and Side EffectsMedically reviewed by Jennie Olopaade, PharmD, RPH
Teva sildenafil is a generic version of Viagra used to treat erectile dysfunction (ED) and some heart conditions.
thumb_upLike (50)
commentReply (2)
thumb_up50 likes
comment
2 replies
L
Luna Park 53 minutes ago
Learn about Teva sildenafil and how…READ MOREHydrocele: Causes, Symptoms, and TreatmentMedically r...
L
Lucas Martinez 34 minutes ago
Xiaflex and Cost: Financial Assistance Options, Savings, More Health ConditionsFeaturedBreast Cancer...
E
Ella Rodriguez Member
access_time
155 minutes ago
Wednesday, 07 May 2025
Learn about Teva sildenafil and how…READ MOREHydrocele: Causes, Symptoms, and TreatmentMedically reviewed by Matt Coward, MD, FACS
A hydrocele is a sac filled with fluid that forms around a testicle. They're usually painless and are most common in babies, but they can affect…READ MORE
thumb_upLike (15)
commentReply (1)
thumb_up15 likes
comment
1 replies
E
Ethan Thomas 41 minutes ago
Xiaflex and Cost: Financial Assistance Options, Savings, More Health ConditionsFeaturedBreast Cancer...