igforum.bio / seki-research-lab-cedars-sinai - 182957
E
%Begin Seki Research Lab Cedars-Sinai Skip to content Close Select your preferred language English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog English English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog Translation is unavailable for Internet Explorer Cedars-Sinai Home 1-800-CEDARS-1 1-800-CEDARS-1 Close Find a Doctor Locations Programs & Services Health Library Patient & Visitors Community My CS-Link RESEARCH clear Go Close Navigation Links Academics Faculty Development Community Engagement Calendar Research Research Areas Research Labs Departments & Institutes Find Clinical Trials Research Cores Research Administration Basic Science Research Clinical & Translational Research Center (CTRC) Technology & Innovations News & Breakthroughs Education Graduate Medical Education Continuing Medical Education Graduate School of Biomedical Sciences Professional Training Programs Medical Students Campus Life Office of the Dean Simulation Center Medical Library Program in the History of Medicine About Us All Education Programs Departments & Institutes Faculty Directory Seki Lab The primary focus of the Seki Laboratory is to understand the role of innate immune and inflammatory signals in chronic liver diseases such as liver fibrosis, alcoholic and nonalcoholic steatohepatitis and hepatocellular carcinoma. In particular, our laboratory is interested in studying the interplay between hepatocytes and non-parenchymal cells (Kupffer cells and hepatic stellate cells) in chronic liver disease. Our research goal is to discover new mechanisms of and novel therapeutic targets for chronic liver disease.
Elijah Patel Member
access_time 3 minutes ago
%Begin Seki Research Lab Cedars-Sinai Skip to content Close Select your preferred language English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog English English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog Translation is unavailable for Internet Explorer Cedars-Sinai Home 1-800-CEDARS-1 1-800-CEDARS-1 Close Find a Doctor Locations Programs & Services Health Library Patient & Visitors Community My CS-Link RESEARCH clear Go Close Navigation Links Academics Faculty Development Community Engagement Calendar Research Research Areas Research Labs Departments & Institutes Find Clinical Trials Research Cores Research Administration Basic Science Research Clinical & Translational Research Center (CTRC) Technology & Innovations News & Breakthroughs Education Graduate Medical Education Continuing Medical Education Graduate School of Biomedical Sciences Professional Training Programs Medical Students Campus Life Office of the Dean Simulation Center Medical Library Program in the History of Medicine About Us All Education Programs Departments & Institutes Faculty Directory Seki Lab The primary focus of the Seki Laboratory is to understand the role of innate immune and inflammatory signals in chronic liver diseases such as liver fibrosis, alcoholic and nonalcoholic steatohepatitis and hepatocellular carcinoma. In particular, our laboratory is interested in studying the interplay between hepatocytes and non-parenchymal cells (Kupffer cells and hepatic stellate cells) in chronic liver disease. Our research goal is to discover new mechanisms of and novel therapeutic targets for chronic liver disease.
thumb_up Like (6)
comment Reply (0)
share Share
visibility 459 views
thumb_up 6 likes
J
The Seki Laboratory is affiliated with the Digestive Diseases Center and the Department of Medicine. Personal Statement Dr.
James Smith Moderator
access_time 6 minutes ago
The Seki Laboratory is affiliated with the Digestive Diseases Center and the Department of Medicine. Personal Statement Dr.
thumb_up Like (11)
comment Reply (3)
thumb_up 11 likes
comment 3 replies
M
Madison Singh 6 minutes ago
Seki’s early research career focused on the study of Toll-like receptors in Kupffer cells. He then...
E
Ethan Thomas 4 minutes ago
Ekihiro Seki, MD, PhD Breakthrough Research Areas Our research team has reported that Toll-like r...
Show 1 more replies
L
Seki’s early research career focused on the study of Toll-like receptors in Kupffer cells. He then combined his immunology research background with the study of chronic liver diseases, including liver fibrosis, alcohol-associated liver disease (ALD), and nonalcoholic fatty liver disease (NAFLD).
Lucas Martinez Moderator
access_time 12 minutes ago
Seki’s early research career focused on the study of Toll-like receptors in Kupffer cells. He then combined his immunology research background with the study of chronic liver diseases, including liver fibrosis, alcohol-associated liver disease (ALD), and nonalcoholic fatty liver disease (NAFLD).
thumb_up Like (7)
comment Reply (0)
thumb_up 7 likes
J
Ekihiro Seki, MD, PhD Breakthrough Research Areas Our research team has reported that Toll-like receptors and intestine-derived bacterial products promote liver fibrosis and fatty liver disease (Seki, et al. Nat Med.
Julia Zhang Member
access_time 20 minutes ago
Ekihiro Seki, MD, PhD Breakthrough Research Areas Our research team has reported that Toll-like receptors and intestine-derived bacterial products promote liver fibrosis and fatty liver disease (Seki, et al. Nat Med.
thumb_up Like (35)
comment Reply (0)
thumb_up 35 likes
S
2007). More recently, we determined that hyaluronan (HA), a biomarker for liver cirrhosis, is the cause and can be a therapeutic target for liver fibrosis (Yang, et al.
Sophia Chen Member
access_time 10 minutes ago
2007). More recently, we determined that hyaluronan (HA), a biomarker for liver cirrhosis, is the cause and can be a therapeutic target for liver fibrosis (Yang, et al.
thumb_up Like (3)
comment Reply (3)
thumb_up 3 likes
comment 3 replies
T
Thomas Anderson 1 minutes ago
Sci Transl Med. 2019). Collaborations Bhowmick Laboratory Freeman Laboratory Gottlieb Laboratory Jia...
H
Harper Kim 4 minutes ago
View Our Team Publications Oral administration of PEGylated TLR7 ligand ameliorates alcohol-assoc...
Show 1 more replies
C
Sci Transl Med. 2019). Collaborations Bhowmick Laboratory Freeman Laboratory Gottlieb Laboratory Jiang Laboratory Lu Laboratory Noble Laboratory Pandol Laboratory Posadas Laboratory Di Vizio Laboratory Sutterwala and Cassel Laboratory Mazen Noureddin, MD Meet Our Team Learn more about the scientists, faculty members, investigators and other healthcare professionals of the Seki Laboratory, whose dedicated efforts lead to groundbreaking discoveries.
Chloe Santos Moderator
access_time 18 minutes ago
Sci Transl Med. 2019). Collaborations Bhowmick Laboratory Freeman Laboratory Gottlieb Laboratory Jiang Laboratory Lu Laboratory Noble Laboratory Pandol Laboratory Posadas Laboratory Di Vizio Laboratory Sutterwala and Cassel Laboratory Mazen Noureddin, MD Meet Our Team Learn more about the scientists, faculty members, investigators and other healthcare professionals of the Seki Laboratory, whose dedicated efforts lead to groundbreaking discoveries.
thumb_up Like (19)
comment Reply (0)
thumb_up 19 likes
J
View Our Team Publications Oral administration of PEGylated TLR7 ligand ameliorates alcohol-associated liver disease via the induction of IL-22 Wang Q, Kim SY, Matsushita H, Wang Z, Pandyarajan V, Matsuda M, Ohashi K, Tsuchiya T, Roh YS, Kiani C, Zhao Y, Chan M, Devkota S, Lu SC, Hayashi T, Carson DA, Seki E. Proc Natl Acad Sci U S A.
Joseph Kim Member
access_time 28 minutes ago
View Our Team Publications Oral administration of PEGylated TLR7 ligand ameliorates alcohol-associated liver disease via the induction of IL-22 Wang Q, Kim SY, Matsushita H, Wang Z, Pandyarajan V, Matsuda M, Ohashi K, Tsuchiya T, Roh YS, Kiani C, Zhao Y, Chan M, Devkota S, Lu SC, Hayashi T, Carson DA, Seki E. Proc Natl Acad Sci U S A.
thumb_up Like (34)
comment Reply (3)
thumb_up 34 likes
comment 3 replies
E
Ella Rodriguez 7 minutes ago
2021 Jan 5;118(1):e2020868118. Hyaluronan synthase 2-mediated hyaluronan production mediates Notch1 ...
C
Christopher Lee 12 minutes ago
Sci Transl Med. 2019;11(496)....
Show 1 more replies
A
2021 Jan 5;118(1):e2020868118. Hyaluronan synthase 2-mediated hyaluronan production mediates Notch1 activation and liver fibrosis. Yang YM, Noureddin M, Liu C, Ohashi K, Kim SY, Ramnath D, Powell EE, Sweet MJ, Roh YS, Hsin IF, Deng N, Liu Z, Liang J, Mena E, Shouhed D, Schwabe RF, Jiang D, Lu SC, Noble PW, Seki E.
Andrew Wilson Member
access_time 40 minutes ago
2021 Jan 5;118(1):e2020868118. Hyaluronan synthase 2-mediated hyaluronan production mediates Notch1 activation and liver fibrosis. Yang YM, Noureddin M, Liu C, Ohashi K, Kim SY, Ramnath D, Powell EE, Sweet MJ, Roh YS, Hsin IF, Deng N, Liu Z, Liang J, Mena E, Shouhed D, Schwabe RF, Jiang D, Lu SC, Noble PW, Seki E.
thumb_up Like (27)
comment Reply (1)
thumb_up 27 likes
comment 1 replies
L
Luna Park 16 minutes ago
Sci Transl Med. 2019;11(496)....
N
Sci Transl Med. 2019;11(496).
Noah Davis Member
access_time 45 minutes ago
Sci Transl Med. 2019;11(496).
thumb_up Like (18)
comment Reply (2)
thumb_up 18 likes
comment 2 replies
L
Lily Watson 6 minutes ago
pii: eaat9284. NOD-like receptor C4 Inflammasome Regulates the Growth of Colon Cancer Liver Metastas...
A
Aria Nguyen 12 minutes ago
Ohashi K, Wang Z, Yang YM, Billet S, Tu W, Pimienta M, Cassel SL, Pandol SJ, Lu SC, Sutterwala FS, B...
A
pii: eaat9284. NOD-like receptor C4 Inflammasome Regulates the Growth of Colon Cancer Liver Metastasis in NAFLD.
Alexander Wang Member
access_time 20 minutes ago
pii: eaat9284. NOD-like receptor C4 Inflammasome Regulates the Growth of Colon Cancer Liver Metastasis in NAFLD.
thumb_up Like (15)
comment Reply (3)
thumb_up 15 likes
comment 3 replies
S
Sophia Chen 6 minutes ago
Ohashi K, Wang Z, Yang YM, Billet S, Tu W, Pimienta M, Cassel SL, Pandol SJ, Lu SC, Sutterwala FS, B...
M
Mia Anderson 18 minutes ago
Murine macrophage autophagy protects against alcohol-induced liver injury by degrading interferon re...
Show 1 more replies
J
Ohashi K, Wang Z, Yang YM, Billet S, Tu W, Pimienta M, Cassel SL, Pandol SJ, Lu SC, Sutterwala FS, Bhowmick N, Seki E. Hepatology. 2019;70(5):1582-1599.
Julia Zhang Member
access_time 33 minutes ago
Ohashi K, Wang Z, Yang YM, Billet S, Tu W, Pimienta M, Cassel SL, Pandol SJ, Lu SC, Sutterwala FS, Bhowmick N, Seki E. Hepatology. 2019;70(5):1582-1599.
thumb_up Like (9)
comment Reply (3)
thumb_up 9 likes
comment 3 replies
W
William Brown 25 minutes ago
Murine macrophage autophagy protects against alcohol-induced liver injury by degrading interferon re...
S
Scarlett Brown 13 minutes ago
2019;294(33):12359-12369. Contact the Seki Lab 8700 Beverly Blvd. Davis Building, Rooms 2099, 2029 L...
Show 1 more replies
E
Murine macrophage autophagy protects against alcohol-induced liver injury by degrading interferon regulatory factor 1 (IRF1) and removing damaged mitochondria. Liang S, Zhong Z, Kim SY, Uchiyama R, Roh YS, Matsushita H, Gottlieb RA, Seki E. J Biol Chem.
Ella Rodriguez Member
access_time 60 minutes ago
Murine macrophage autophagy protects against alcohol-induced liver injury by degrading interferon regulatory factor 1 (IRF1) and removing damaged mitochondria. Liang S, Zhong Z, Kim SY, Uchiyama R, Roh YS, Matsushita H, Gottlieb RA, Seki E. J Biol Chem.
thumb_up Like (28)
comment Reply (0)
thumb_up 28 likes
A
2019;294(33):12359-12369. Contact the Seki Lab 8700 Beverly Blvd. Davis Building, Rooms 2099, 2029 Los Angeles, CA 90048 310-423-6605 Send A Message Please ensure Javascript is enabled for purposes of website accessibility
Alexander Wang Member
access_time 13 minutes ago
2019;294(33):12359-12369. Contact the Seki Lab 8700 Beverly Blvd. Davis Building, Rooms 2099, 2029 Los Angeles, CA 90048 310-423-6605 Send A Message Please ensure Javascript is enabled for purposes of website accessibility
thumb_up Like (20)
comment Reply (0)
thumb_up 20 likes

Write a Reply

Similar Discussions