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%Begin Oncology Medical - Clinical trials - Mayo Clinic <h2>COVID-19 Advice updates and vaccine options</h2> Find out about COVID-19, COVID-19 vaccines, and Mayo Clinic patient and visitor updates. Skip to site navigation Skip to Content This content does not have an English version.This content does not have an Arabic version.
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%Begin Oncology Medical - Clinical trials - Mayo Clinic

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Charlotte Lee 3 minutes ago
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Daniel Kumar 1 minutes ago

A Study of Vulvovaginal Symptoms in Premenopausal Stage 0-III Breast Cancer Patients Treated on ...

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Search Request an Appointment Find a Doctor Find a Job Give Now Log in to Patient Account English Español العربية 简体中文 Twitter Facebook Pinterest YouTube Menu Request an Appointment Departments & Centers Medical Departments & Centers <h1>Oncology Medical </h1> <h2>Clinical trials</h2> Below are current clinical trials.<br>434 studies in Oncology Medical <br> (open studies only). Filter this list of studies by location, status and more.
Julia Zhang Member
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Oncology Medical

Clinical trials

Below are current clinical trials.
434 studies in Oncology Medical
(open studies only). Filter this list of studies by location, status and more.
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Ava White 3 minutes ago

A Study of Vulvovaginal Symptoms in Premenopausal Stage 0-III Breast Cancer Patients Treated on ...

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Ethan Thomas 1 minutes ago

DSC-MRI in Measuring Relative Cerebral Blood Volume for Early Response to Bevacizumab in Patient...

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<h3>A Study of Vulvovaginal Symptoms in Premenopausal Stage 0-III Breast Cancer Patients Treated on Aromatase Inhibitors and Ovarian Suppression</h3> Jacksonville, Fla. The purpose of this study is to evaluate the change of vulvovaginal symptoms score from baseline to 6 months in premenopausal women with stage 0-III breast cancer treating with ovarian suppression in combination with aromatase inhibitors.
James Smith Moderator
access_time 12 minutes ago

A Study of Vulvovaginal Symptoms in Premenopausal Stage 0-III Breast Cancer Patients Treated on Aromatase Inhibitors and Ovarian Suppression

Jacksonville, Fla. The purpose of this study is to evaluate the change of vulvovaginal symptoms score from baseline to 6 months in premenopausal women with stage 0-III breast cancer treating with ovarian suppression in combination with aromatase inhibitors.
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Grace Liu 8 minutes ago

DSC-MRI in Measuring Relative Cerebral Blood Volume for Early Response to Bevacizumab in Patient...

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<h3>DSC-MRI in Measuring Relative Cerebral Blood Volume for Early Response to Bevacizumab in Patients With Recurrent Glioblastoma</h3> Rochester, Minn., Scottsdale/Phoenix, Ariz., Jacksonville, Fla. This phase II trial studies how well dynamic susceptibility contrast-enhanced magnetic resonance imaging (DSC-MRI) works in measuring relative cerebral blood volume (rCBV) for early response to bevacizumab in patients with glioblastoma that has come back.
Natalie Lopez Member
access_time 12 minutes ago

DSC-MRI in Measuring Relative Cerebral Blood Volume for Early Response to Bevacizumab in Patients With Recurrent Glioblastoma

Rochester, Minn., Scottsdale/Phoenix, Ariz., Jacksonville, Fla. This phase II trial studies how well dynamic susceptibility contrast-enhanced magnetic resonance imaging (DSC-MRI) works in measuring relative cerebral blood volume (rCBV) for early response to bevacizumab in patients with glioblastoma that has come back.
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DSC-MRI may help evaluate changes in the blood vessels within the cancer to determine a patient?s response to treatment. <h3>A Study to Determine the Best Individualized Cancer Therapy Using Circulating Tumor DNA ctDNA in Patients with GI CNS and Thoracic Cancers </h3> Jacksonville, Fla.
Luna Park Member
access_time 25 minutes ago
DSC-MRI may help evaluate changes in the blood vessels within the cancer to determine a patient?s response to treatment.

A Study to Determine the Best Individualized Cancer Therapy Using Circulating Tumor DNA ctDNA in Patients with GI CNS and Thoracic Cancers

Jacksonville, Fla.
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This study proposes to develop and maintain a biorepository of blood samples collected from patients receiving definitive chemoradiotherapy for locally advanced rectal cancer, locally advanced pancreatic cancer, non-small cell lung cancer, or cervical cancer. The ultimate goal of this biorepository will be to provide the resource to initiate an exploration of ctDNA as a potential liquid biopsy for GI and Thoracic malignancy detection and surveillance.
Kevin Wang Member
access_time 24 minutes ago
This study proposes to develop and maintain a biorepository of blood samples collected from patients receiving definitive chemoradiotherapy for locally advanced rectal cancer, locally advanced pancreatic cancer, non-small cell lung cancer, or cervical cancer. The ultimate goal of this biorepository will be to provide the resource to initiate an exploration of ctDNA as a potential liquid biopsy for GI and Thoracic malignancy detection and surveillance.
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<h3>Cutaneous Lymphoma Database</h3> Scottsdale/Phoenix, Ariz. The purpose of this study is to create a &nbsp;long-term, prospective database of cutaneous lymphoma that&nbsp;will&nbsp;lead to a better understanding of the biological behavior of cutaneous lymphomas as well as the effectiveness of interventions. <h3>A Study to Evaluate a Health and Wellness Coaching Model in Support of Caregivers of Patients with Advanced Lung Cancers</h3> Jacksonville, Fla.
Dylan Patel Member
access_time 28 minutes ago

Cutaneous Lymphoma Database

Scottsdale/Phoenix, Ariz. The purpose of this study is to create a  long-term, prospective database of cutaneous lymphoma that will lead to a better understanding of the biological behavior of cutaneous lymphomas as well as the effectiveness of interventions.

A Study to Evaluate a Health and Wellness Coaching Model in Support of Caregivers of Patients with Advanced Lung Cancers

Jacksonville, Fla.
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Andrew Wilson 5 minutes ago
Piloting the BeWell360-CG model, in conjunction with usual care delivery for lung cancer patients in...
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Charlotte Lee 1 minutes ago
The objective of this proposal is to pilot a novel, scalable, user-friendly HWC care model– the Be...
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Piloting the BeWell360-CG model, in conjunction with usual care delivery for lung cancer patients in Palliative Care, will longitudinally improve the wellbeing and quality of life of care givers within and outside of clinical care settings, in such a way as to positively impact the quality of care of patients themselves. We hypothesize that PC staff trained in the BeWell360-CG will be able to identify the most common CG-centric needs and guide CGs to improve their QoL and personal wellbeing. In doing so, we further hypothesize that there will be an improvement in patient-reported and quality of care outcomes.
Oliver Taylor Member
access_time 24 minutes ago
Piloting the BeWell360-CG model, in conjunction with usual care delivery for lung cancer patients in Palliative Care, will longitudinally improve the wellbeing and quality of life of care givers within and outside of clinical care settings, in such a way as to positively impact the quality of care of patients themselves. We hypothesize that PC staff trained in the BeWell360-CG will be able to identify the most common CG-centric needs and guide CGs to improve their QoL and personal wellbeing. In doing so, we further hypothesize that there will be an improvement in patient-reported and quality of care outcomes.
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The objective of this proposal is to pilot a novel, scalable, user-friendly HWC care model– the BeWell360-CG— that is embedded and integrated as part of a palliative approach to care for CGs of patients with advanced lung cancer. <h3>A Study to Evaluate Exemestane in Post-Menopausal Women with Non-Small Cell Lung Cancer NSCLC </h3> Albert Lea, Minn., Mankato, Minn. This study is being conducted to see if adding Exemestane to the immune checkpoint blockade can slow disease progression in post-menopausal women with non-small cell lung cancer.
David Cohen Member
access_time 36 minutes ago
The objective of this proposal is to pilot a novel, scalable, user-friendly HWC care model– the BeWell360-CG— that is embedded and integrated as part of a palliative approach to care for CGs of patients with advanced lung cancer.

A Study to Evaluate Exemestane in Post-Menopausal Women with Non-Small Cell Lung Cancer NSCLC

Albert Lea, Minn., Mankato, Minn. This study is being conducted to see if adding Exemestane to the immune checkpoint blockade can slow disease progression in post-menopausal women with non-small cell lung cancer.
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<h3>Perioperative Enfortumab Vedotin EV Plus Pembrolizumab MK-3475 Versus Neoadjuvant Chemotherapy for Cisplatin-eligible Muscle Invasive Bladder Cancer MIBC MK-3475-B15 KEYNOTE-B15 EV-304 </h3> Scottsdale/Phoenix, Ariz. The purpose of this study is to assess the antitumor effectiveness and safety of perioperative enfortumab vedotin (EV) plus pembrolizumab and radical cystectomy (RC) + pelvic lymph node dissection (PLND) compared with the current standard of care (neoadjuvant chemotherapy [gemcitabine plus cisplatin] and RC + PLND) for participants with MIBC who are cisplatin-eligible.
Noah Davis Member
access_time 10 minutes ago

Perioperative Enfortumab Vedotin EV Plus Pembrolizumab MK-3475 Versus Neoadjuvant Chemotherapy for Cisplatin-eligible Muscle Invasive Bladder Cancer MIBC MK-3475-B15 KEYNOTE-B15 EV-304

Scottsdale/Phoenix, Ariz. The purpose of this study is to assess the antitumor effectiveness and safety of perioperative enfortumab vedotin (EV) plus pembrolizumab and radical cystectomy (RC) + pelvic lymph node dissection (PLND) compared with the current standard of care (neoadjuvant chemotherapy [gemcitabine plus cisplatin] and RC + PLND) for participants with MIBC who are cisplatin-eligible.
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Scarlett Brown 5 minutes ago
The dual primary hypotheses are preoperative EV + pembrolizumab and RC + PLND (Arm A) will achieve s...
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Joseph Kim 3 minutes ago
manual tracing. These aims will be evaluated in a clinical environment to investigate the impact of ...
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The dual primary hypotheses are preoperative EV + pembrolizumab and RC + PLND (Arm A) will achieve superior pathologic complete response (pCR) rate and perioperative EV and pembrolizumab and RC + PLND (Arm A) will achieve superior event free survival (EFS) compared with neoadjuvant gemcitabine + cisplatin and RC + PLND (Arm B). <h3>A Study to Evaluate Contouring Organs at Risk for Treatment Planning</h3> Scottsdale/Phoenix, Ariz., Jacksonville, Fla., Rochester, Minn. The purpose of this study is to determine: if the artificial intelligence (AI)-generated results are less arduous than manual tracing by radiation oncologist, and the non-inferiority of the quality of AI vs.
Ella Rodriguez Member
access_time 33 minutes ago
The dual primary hypotheses are preoperative EV + pembrolizumab and RC + PLND (Arm A) will achieve superior pathologic complete response (pCR) rate and perioperative EV and pembrolizumab and RC + PLND (Arm A) will achieve superior event free survival (EFS) compared with neoadjuvant gemcitabine + cisplatin and RC + PLND (Arm B).

A Study to Evaluate Contouring Organs at Risk for Treatment Planning

Scottsdale/Phoenix, Ariz., Jacksonville, Fla., Rochester, Minn. The purpose of this study is to determine: if the artificial intelligence (AI)-generated results are less arduous than manual tracing by radiation oncologist, and the non-inferiority of the quality of AI vs.
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Sophie Martin 3 minutes ago
manual tracing. These aims will be evaluated in a clinical environment to investigate the impact of ...
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Charlotte Lee 3 minutes ago
Radiotherapy treatment planning requires precise calculations of radiation exposure, not only for th...
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manual tracing. These aims will be evaluated in a clinical environment to investigate the impact of an AI algorithm on the clinical workflow.
Audrey Mueller Member
access_time 12 minutes ago
manual tracing. These aims will be evaluated in a clinical environment to investigate the impact of an AI algorithm on the clinical workflow.
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Andrew Wilson 11 minutes ago
Radiotherapy treatment planning requires precise calculations of radiation exposure, not only for th...
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Chloe Santos 2 minutes ago

A Study to Evaluate Immunotherapy for Non-Small Cell Lung Cancer

Scottsdale/Phoenix, Ariz. ...
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Radiotherapy treatment planning requires precise calculations of radiation exposure, not only for the target volumes (tissue containing malignancy), but of nearby organs-at-risk (OARs), in which the exposure needs to be minimized. Manual segmentation of these organs is a time-consuming task with high interobserver variability. Producing these segmentations automatically will reduce the time required for treatment planning and improve the interobserver variability.
Liam Wilson Member
access_time 13 minutes ago
Radiotherapy treatment planning requires precise calculations of radiation exposure, not only for the target volumes (tissue containing malignancy), but of nearby organs-at-risk (OARs), in which the exposure needs to be minimized. Manual segmentation of these organs is a time-consuming task with high interobserver variability. Producing these segmentations automatically will reduce the time required for treatment planning and improve the interobserver variability.
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Sophie Martin 6 minutes ago

A Study to Evaluate Immunotherapy for Non-Small Cell Lung Cancer

Scottsdale/Phoenix, Ariz. ...
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Thomas Anderson 7 minutes ago
The purposes of this study are to analyze the ovarian function of female premenopausal melanoma sur...
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<h3>A Study to Evaluate Immunotherapy for Non-Small Cell Lung Cancer</h3> Scottsdale/Phoenix, Ariz. The primary objectives of this study are to evaluate safety/tolerability and immunogenicity of IMU-201 as monotherapy and in combination with an immune checkpoint inhibitor (ICI) or an ICI and chemotherapy in participants with advanced NSCLC tumors that are positive for PD-L1, and to identify the Optimal Biological Dose (OBD) of IMU-201 as monotherapy and in combination with an ICI, or an ICI and chemotherapy, in participants with advanced NSCLC tumors that are positive for PD-L1. <h3>A Study to Evaluate Immunotherapy and Ovarian Function Among Pre-menopausal Melanoma Survivors</h3> Rochester, Minn.
Scarlett Brown Member
access_time 42 minutes ago

A Study to Evaluate Immunotherapy for Non-Small Cell Lung Cancer

Scottsdale/Phoenix, Ariz. The primary objectives of this study are to evaluate safety/tolerability and immunogenicity of IMU-201 as monotherapy and in combination with an immune checkpoint inhibitor (ICI) or an ICI and chemotherapy in participants with advanced NSCLC tumors that are positive for PD-L1, and to identify the Optimal Biological Dose (OBD) of IMU-201 as monotherapy and in combination with an ICI, or an ICI and chemotherapy, in participants with advanced NSCLC tumors that are positive for PD-L1.

A Study to Evaluate Immunotherapy and Ovarian Function Among Pre-menopausal Melanoma Survivors

Rochester, Minn.
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Emma Wilson 11 minutes ago
The purposes of this study are to analyze the ovarian function of female premenopausal melanoma sur...
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Mayo Clinic in Rochester Minnesota and Mayo Clinic in Ph...

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The purposes of this study are to analyze the ovarian function of female premenopausal melanoma survivors who have undergone immunotherapy, and compare with data from age-matched controls, prospectively investigate ovarian function in premenopausal women with melanoma undergoing immunotherapy, and to identify the impact of ovarian function change on the frequency and function of CD8+ T cells during immunotherapy. Request an Appointment at Mayo Clinic Locations, travel & lodgingResearch Oct.
Julia Zhang Member
access_time 15 minutes ago
The purposes of this study are to analyze the ovarian function of female premenopausal melanoma survivors who have undergone immunotherapy, and compare with data from age-matched controls, prospectively investigate ovarian function in premenopausal women with melanoma undergoing immunotherapy, and to identify the impact of ovarian function change on the frequency and function of CD8+ T cells during immunotherapy. Request an Appointment at Mayo Clinic Locations, travel & lodgingResearch Oct.
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Lily Watson 11 minutes ago
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11, 2022 Share on: FacebookTwitter <h3> Mayo Clinic in Rochester Minnesota and Mayo Clinic in Phoenix Scottsdale Arizona have been recognized among the top Cancer hospitals in the nation for 2022-2023 by U S News &amp World Report </h3> Learn more about this top honor <h2>Oncology Medical </h2>Department homeSectionsRequest an appointmentOverviewConditions treatedDoctorsSpecialty groupsExpertise & rankingsLocations, travel & lodgingClinical trialsResearchThe Mayo Clinic experience & patient storiesCosts & insuranceNews from Mayo ClinicReferrals <h3>Research It s All About Patients</h3> <h2>Sections</h2>Request an appointmentOverviewConditions treatedDoctorsSpecialty groupsExpertise & rankingsLocations, travel & lodgingClinical trialsResearchThe Mayo Clinic experience & patient storiesCosts & insuranceNews from Mayo ClinicReferrals ORG-20180179 Departments & Centers Medical Departments & Centers Oncology Medical
Lucas Martinez Moderator
access_time 32 minutes ago
11, 2022 Share on: FacebookTwitter

Mayo Clinic in Rochester Minnesota and Mayo Clinic in Phoenix Scottsdale Arizona have been recognized among the top Cancer hospitals in the nation for 2022-2023 by U S News & World Report

Learn more about this top honor

Oncology Medical

Department homeSectionsRequest an appointmentOverviewConditions treatedDoctorsSpecialty groupsExpertise & rankingsLocations, travel & lodgingClinical trialsResearchThe Mayo Clinic experience & patient storiesCosts & insuranceNews from Mayo ClinicReferrals

Research It s All About Patients

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Request an appointmentOverviewConditions treatedDoctorsSpecialty groupsExpertise & rankingsLocations, travel & lodgingClinical trialsResearchThe Mayo Clinic experience & patient storiesCosts & insuranceNews from Mayo ClinicReferrals ORG-20180179 Departments & Centers Medical Departments & Centers Oncology Medical
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