L
%Begin Nocdurna: Side effects, dosage, alternatives, cost, and more Health ConditionsHealth ConditionsAlzheimer's & DementiaAnxietyArthritisAsthma & AllergiesBreast CancerCancerCardiovascular HealthCOVID-19Dermatology & SkincareDiabetesEnvironment & SustainabilityExercise & FitnessEye HealthHeadache & MigraineHealth EquityHIV & AIDSHuman BiologyInflammatory Bowel DiseaseLeukemiaLGBTQIA+Men's HealthMental HealthMultiple Sclerosis (MS)NutritionParkinson's DiseasePsoriasisSexual HealthWomen's HealthDiscoverNewsLatest NewsOriginal SeriesMedical MythsHonest NutritionThrough My EyesNew Normal HealthPodcastsHow to understand chronic painWhat is behind vaccine hesitancy?The amazing story of hepatitis C, from discovery to cureNew directions in dementia researchCan psychedelics rewire a depressed, anxious brain?Why climate change matters for human healthToolsGeneral HealthDrugs A-ZHealth HubsHealth ToolsBMI Calculators and ChartsBlood Pressure Chart: Ranges and GuideBreast Cancer: Self-Examination GuideSleep CalculatorHealth ProductsAffordable Therapy OptionsBlood Pressure MonitorsDiabetic SuppliesFitness TrackersHome GymsGreen Cleaning ProductsHow to Shop for CBDQuizzesRA Myths vs FactsType 2 Diabetes: Managing Blood SugarAnkylosing Spondylitis Pain: Fact or FictionConnectAbout Medical News TodayWho We AreOur Editorial ProcessContent IntegrityConscious LanguageNewslettersSign UpFollow UsMedical News TodayHealth ConditionsDiscoverToolsConnectSubscribe
Nocdurna desmopressin acetate Medically reviewed by Melissa Badowski, PharmD, MPH, FCCP — By Patricia Weiser, PharmD on August 22, 2022
What is Nocdurna Nocdurna is a brand-name prescription drug. It’s FDA-approved to treat nocturia (frequent urination at night) in adults. Specifically, Nocdurna is approved for use in people who wake up at least twice to urinate due to nocturnal polyuria.
visibility
624 views
thumb_up
14 likes
R
(With nocturnal polyuria, your kidneys make too much urine at night.)
Drug details
Nocdurna comes as a sublingual tablet (a tablet you dissolve under your tongue). This drug comes in two strengths: 27.7 micrograms (mcg) and 55.3 mcg.
thumb_up
31 likes
A
Nocdurna belongs to a group of drugs called antidiuretics. To learn more about how this drug works, see the “How Nocdurna works” section below. Effectiveness
For information about the effectiveness of Nocdurna, see the “Nocdurna uses” section below.
thumb_up
3 likes
A
Nocdurna generic
Nocdurna is available only as a brand-name medication. It’s not currently available in a generic version.
thumb_up
0 likes
W
Nocdurna contains the active ingredient desmopressin acetate. Other versions of desmopressin acetate are available as generic drugs in different forms.
thumb_up
15 likes
N
These include an oral tablet, an injection, and a nasal spray. A generic drug is an exact copy of the active drug in a brand-name medication. Generics typically cost less than brand-name drugs.
thumb_up
42 likes
L
If you’re interested in using a generic version of desmopressin acetate, talk with your doctor. They can tell you if it comes in forms and strengths that are suitable for treating your condition. Nocdurna side effects
Nocdurna can cause mild or serious side effects.
thumb_up
5 likes
L
The following lists contain some of the key side effects that may occur while taking Nocdurna. These lists do not include all possible side effects. For more information about the possible side effects of Nocdurna, talk with your doctor or pharmacist.
thumb_up
20 likes
A
They can give you tips on how to manage any side effects that may be concerning or bothersome. Note: The Food and Drug Administration (FDA) tracks side effects of drugs it has approved.
thumb_up
8 likes
E
If you would like to notify the FDA about a side effect you’ve had with Nocdurna, you can do so through MedWatch. Mild side effects
Mild side effects* of Nocdurna can include:dry mouthdizzinessheadachemild allergic reaction†
Most of these side effects may go away within a few days to a couple of weeks. However, if they become more severe or don’t go away, talk with your doctor or pharmacist.
thumb_up
1 likes
C
* This is a partial list of mild side effects from Nocdurna. To learn about other mild side effects, talk with your doctor or pharmacist, or view Nocdurna’s prescribing information.
thumb_up
46 likes
A
† To learn more about this side effect, see “Allergic reaction” below. Serious side effects
Serious side effects from Nocdurna aren’t common, but they can occur.
thumb_up
13 likes
H
Call your doctor right away if you have serious side effects. Call 911 or your local emergency number if your symptoms feel life threatening or if you think you’re having a medical emergency.
thumb_up
16 likes
S
Serious side effects and their symptoms can include:Edema (fluid buildup). Symptoms may include:swelling, especially in the lower legs and feetbloatingweight gainHyponatremia (low blood sodium [salt] level).*Severe allergic reaction.† * Nocdurna has a boxed warning for this side effect. This is a serious warning from the FDA.
thumb_up
34 likes
W
To learn more, see the “Nocdurna precautions” section below. † To learn more about this side effect, see “Allergic reaction” below.
thumb_up
47 likes
A
ALLERGIC REACTION
As with most drugs, some people can have an allergic reaction after taking Nocdurna. This side effect wasn’t reported in clinical trials of the drug, but it can still occur. Symptoms of a mild allergic reaction can include:skin rashitchinessflushing
A more severe allergic reaction is rare but possible.
thumb_up
42 likes
E
Symptoms of a severe allergic reaction can include:swelling under your skin, typically in your eyelids, lips, hands, or feetswelling of your tongue, mouth, or throattrouble breathing
Call your doctor right away if you have an allergic reaction to Nocdurna, as the reaction could become severe. Call 911 or your local emergency number if your symptoms feel life threatening or if you think you’re having a medical emergency. Nocdurna dosage
The Nocdurna dosage your doctor prescribes will depend on your assigned sex.
thumb_up
8 likes
T
(Sex and gender exist on spectrums. Use of the terms “male” and “female” in this article refers to sex assigned at birth.)
The following information describes dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you.
thumb_up
47 likes
N
Your doctor will determine the best dosage to fit your needs. Drug forms and strengths
Nocdurna comes as a sublingual tablet (a tablet that dissolves under your tongue). The drug comes in two strengths:27.7 micrograms (mcg), equal to 25 mcg of desmopressin*55.3 mcg, equal to 50 mcg of desmopressin
Dosage for nocturia
The typical dosage of Nocdurna for nocturia (frequent urination at night) is one dose per day.
thumb_up
40 likes
M
You’ll take your dose 1 hour before bedtime, without water. Be sure to urinate right before you go to bed.
thumb_up
16 likes
S
(For more details, see the “How to take Nocdurna” section below.)
The recommended dose of Nocdurna for males is 55.3 mcg. And the recommended dose of Nocdurna for females is 27.7 mcg.
thumb_up
24 likes
E
What if I miss a dose
If you forget to take Nocdurna an hour before bedtime, you can take it as soon as you remember that night, without water. However, if you miss taking a dose, just skip the missed dose.
thumb_up
3 likes
B
You should not take more than one dose of Nocdurna at a time. Doing so may lead to hyponatremia (low blood sodium [salt] level), a serious side effect.†
To help make sure that you don’t miss a dose, try using a medication reminder. This can include setting an alarm or using a timer.
thumb_up
24 likes
W
You could also download a reminder app on your phone. Will I need to use this drug long term
Nocdurna is typically a long-term treatment.
thumb_up
13 likes
L
If you and your doctor determine that Nocdurna is safe and effective for you, you’ll likely take it long term. * Desmopressin is an analog (synthetic version) of a hormone that’s made in your body. When you take Nocdurna, your body absorbs Nocdurna’s active ingredient, desmopressin acetate, as desmopressin.
thumb_up
30 likes
A
For more details, see the “How Nocdurna works” section below. † Nocdurna has a boxed warning for this side effect.
thumb_up
14 likes
M
This is a serious warning from the Food and Drug Administration (FDA). To learn more, see the “Nocdurna precautions” section below. Alternatives to Nocdurna
Other drugs are available that can treat your condition.
thumb_up
19 likes
S
Some may be a better fit for you than others. If you’re interested in finding an alternative to Nocdurna, talk with your doctor.
thumb_up
50 likes
G
They can tell you about options that may work well for you. Note: Some of the drugs listed here are used off-label to treat these specific conditions. Off-label drug use is when a drug that’s approved by the Food and Drug Administration (FDA) is prescribed for a purpose other than what it’s approved for.
thumb_up
38 likes
E
Alternatives for nocturia
Examples of other drugs that may be used to treat nocturia (frequent urination at night) include:imipramine (Tofranil)hyoscyamine (Levsin)oxybutynin (Ditropan XL)desmopressin acetate oral tabletdesmopressin acetate nasal spray
Note: The active ingredient in Nocdurna, desmopressin acetate, was previously available as the brand-name nasal spray drugs Noctiva and Minirin. These drugs are currently discontinued and not available for use. At this time, desmopressin acetate nasal spray is available only as a generic drug.
thumb_up
2 likes
J
Nocdurna cost
As with all medications, the cost of Nocdurna can vary. To find current prices for Nocdurna in your area, check out GoodRx.com. The cost you find on GoodRx.com is what you may pay without insurance.
thumb_up
2 likes
S
The actual price you’ll pay depends on your insurance plan, your location, and the pharmacy you use. Keep in mind that you may be able to get a 90-day supply of Nocdurna. If approved by your insurance company, getting a 90-day supply of the drug could reduce your number of trips to the pharmacy and help lower the cost.
thumb_up
48 likes
C
If you’re interested in this option, check with your doctor, pharmacist, or insurance company. Before approving coverage for Nocdurna, your insurance company may require you to get prior authorization. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug.
thumb_up
46 likes
E
The insurance company will review the prior authorization request and decide if the drug will be covered. If you’re not sure if you’ll need to get prior authorization for Nocdurna, contact your insurance company. Financial and insurance assistance
If you need financial support to pay for Nocdurna or help understanding your insurance coverage, help is available.
thumb_up
8 likes
S
A copay card is available for Nocdurna. For more information and to find out if you’re eligible for support, visit the program website. To learn more about saving money on prescriptions, check out this article.
thumb_up
31 likes
L
Mail-order pharmacies
Nocdurna may be available through a mail-order pharmacy. Using this service may help lower the drug’s cost and allow you to get your medication without leaving home.
thumb_up
39 likes
C
If recommended by your doctor, you may be able to receive a 90-day supply of Nocdurna, so there’s less concern about running out of the medication. If you’re interested in this option, check with your doctor, pharmacist, or insurance company.
thumb_up
49 likes
J
Some Medicare plans may help cover the cost of mail-order medications. If you don’t have insurance, you can ask your doctor or pharmacist about online pharmacy options.
thumb_up
7 likes
J
Generic version
Nocdurna is available only as a brand-name medication. It contains the active ingredient desmopressin acetate. Other versions of desmopressin acetate are available as generic drugs in different forms.
thumb_up
42 likes
A
These include an oral tablet, an injection, and a nasal spray. A generic drug is an exact copy of the active drug in a brand-name medication. Generic drugs are just as safe and effective as the original drug.
thumb_up
41 likes
N
And generics typically cost less than brand-name drugs. If you’re interested in using a generic alternative to Nocdurna, talk with your doctor. They can tell you if another form of desmopressin acetate might be suitable for treating your condition.
thumb_up
16 likes
E
Nocdurna uses
The Food and Drug Administration (FDA) approves prescription drugs such as Nocdurna to treat certain conditions. Nocdurna may also be used off-label for other conditions. Off-label drug use is when an FDA-approved drug is prescribed for a purpose other than what it’s approved for.
thumb_up
41 likes
H
Nocdurna for nocturia
Nocdurna is FDA-approved to treat nocturia (frequent urination at night) in adults. Specifically, it’s prescribed to people who wake up at least twice to urinate due to nocturnal polyuria.
thumb_up
12 likes
M
Nocturnal polyuria explained
With nocturnal polyuria, your kidneys make too much urine at night. People with this condition often wake up more than once to urinate. Nocturnal polyuria can cause sleep disruptions, which can lead to daytime sleepiness and less mental alertness.
thumb_up
40 likes
H
Getting up to go to the bathroom at night can also lead to falls and injuries, especially in older adults. Nocturnal polyuria is caused by low levels of antidiuretic hormone (ADH) at night, among other factors. ADH is also called vasopressin.
thumb_up
38 likes
L
Nocdurna works by mimicking the natural effects of vasopressin. The drug helps your kidneys store water instead of getting rid of it in urine. This leads to less urine production at night.
thumb_up
8 likes
A
Before prescribing Nocdurna, your doctor may have you do a 24-hour urine collection to help confirm you have nocturnal polyuria. With this test, you’ll collect your urine and record what times you urinate over 24 hours. Your doctor may diagnose nocturnal polyuria if:you collected more than a third of your total urine at nightthere are no other causes of nocturia, such as drinking a lot of fluids before bed
If you have questions about your condition, talk with your doctor.
thumb_up
29 likes
N
Effectiveness for nocturia
In clinical trials, Nocdurna has been shown to be an effective treatment for nocturia in adults who have nocturnal polyuria. To learn how Nocdurna performed in clinical trials, see the drug’s prescribing information. Nocdurna and children
Nocdurna is only approved for use in adults.
thumb_up
6 likes
L
If your child has frequent urination at night, talk with their doctor about possible treatment options. Nocdurna and alcohol
There are no known interactions between Nocdurna and alcohol. However, you should avoid drinking alcohol close to bedtime while taking Nocdurna.
thumb_up
50 likes
N
Alcohol can cause your body to make more urine than usual. So, drinking alcohol with Nocdurna may make this medication less effective.
thumb_up
24 likes
M
Remember that Nocdurna is meant to help your body produce less urine at night. (For more information, see the “Nocdurna uses” section above.)
In fact, you should limit your intake of any fluid from 1 hour before taking Nocdurna until 8 hours afterward.
thumb_up
38 likes
D
Drinking too much water or other liquids with Nocdurna can increase the risk of hyponatremia (low blood sodium [salt] level), a serious side effect.*
If you drink alcohol, talk with your doctor about when and how much is safe for you to drink while taking Nocdurna. * Nocdurna has a boxed warning for this side effect. This is a serious warning from the Food and Drug Administration (FDA).
thumb_up
33 likes
I
To learn more, see the “Nocdurna precautions” section below. Nocdurna interactions
Nocdurna can interact with several other medications.
thumb_up
30 likes
A
Different interactions can cause different effects. For instance, some interactions can interfere with how well a drug works.
thumb_up
21 likes
M
Other interactions can increase side effects or make them more severe. Drug-condition interactions can also cause certain effects. For information about these interactions, see the “Nocdurna precautions” section below.
thumb_up
12 likes
H
Nocdurna and other medications
Below is a list of medications that can interact with Nocdurna. This list does not contain all drugs that may interact with it.
thumb_up
23 likes
A
Before taking Nocdurna, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use.
thumb_up
3 likes
I
Sharing this information can help you avoid potential interactions. Certain drugs are known to increase the risk of hyponatremia (low blood sodium [salt] level), a possible serious side effect of Nocdurna.* Due to this risk, doctors typically will not prescribe Nocdurna with:loop diuretics, such as furosemide (Lasix) and bumetanide (Bumex)systemic† glucocorticoids, such as prednisone (Rayos) and methylprednisolone (Solu-Medrol)inhaled glucocorticoids, such as budesonide (Pulmicort Flexhaler) and fluticasone (Flovent HFA)
Other drugs could also increase the risk of hyponatremia when taken with Nocdurna.
thumb_up
47 likes
C
Your doctor may monitor you closely during Nocdurna treatment if you also take:tricyclic antidepressants, such as amitriptylineselective serotonin reuptake inhibitors, such as escitalopram (Lexapro)nonsteroidal anti-inflammatory drugs, such as ibuprofen (Advil, Motrin) and naproxen (Aleve)chlorpromazine, an antipsychotic drugopiate pain medications, such as morphine (MS Contin) and codeinecarbamazepine (Carbatrol, Equetro, Tegretol, others)lamotrigine (Lamictal)thiazide diuretics, such as hydrochlorothiazide (Microzide)sulfonylureas (a group of diabetes drugs), such as glipizide (Glucotrol XL)
If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. * Nocdurna has a boxed warning for this side effect.
thumb_up
37 likes
K
This is a serious warning from the Food and Drug Administration (FDA). To learn more, see the “Nocdurna precautions” section below. † “Systemic” refers to drugs given by mouth or by injection that affect the entire body.
thumb_up
42 likes
J
Nocdurna and herbs and supplements
There aren’t any herbs or supplements that have been specifically reported to interact with Nocdurna. However, you should still check with your doctor or pharmacist before using any of these products while taking Nocdurna. Nocdurna and foods
There aren’t any foods that have been specifically reported to interact with Nocdurna.
thumb_up
27 likes
A
However, doctors typically recommend avoiding drinks that contain caffeine before bedtime when taking Nocdurna. Not only can caffeine affect your sleep, but it may make Nocdurna less effective.
thumb_up
5 likes
L
This is because caffeine can cause your body to make more urine. And Nocdurna is meant to help your kidneys produce less urine at night. (For more information, see the “Nocdurna uses” section above.)
If you have any questions about having certain foods or drinks that contain caffeine while taking Nocdurna, talk with your doctor.
thumb_up
31 likes
A
How to take Nocdurna
Nocdurna comes as a sublingual tablet (a tablet that dissolves under your tongue). You should take Nocdurna according to the instructions your doctor gives you. To take Nocdurna, place one tablet under your tongue.
thumb_up
36 likes
M
Keep it under your tongue until it completely dissolves. Typically, this will happen within seconds.
thumb_up
19 likes
H
Do not swallow the tablet. Be sure to take Nocdurna without water and empty your bladder right before you go to sleep.
thumb_up
15 likes
I
Also, limit the amount of water or fluids you drink for 1 hour before your dose and until 8 hours after your dose. When to take
You’ll take Nocdurna once per day, 1 hour before bedtime. To help make sure that you don’t miss a dose, try using a medication reminder.
thumb_up
18 likes
B
This can include setting an alarm or using a timer. You could also download a reminder app on your phone. Accessible labels and containers
If your prescription label is hard to read, talk with your doctor or pharmacist.
thumb_up
7 likes
C
Some pharmacies offer labels that have large print, braille, or a code you scan with a smartphone to convert text to speech. If your local pharmacy doesn’t have these options, your doctor or pharmacist may be able to direct you to one that does.
thumb_up
26 likes
A
Taking Nocdurna with food
You should avoid eating food and drinking fluids for 1 hour before your Nocdurna dose and for 8 hours after your dose. This is because many foods contain water.
thumb_up
20 likes
C
And consuming too much fluid with Nocdurna can increase the risk of hyponatremia (low blood sodium [salt] level), a serious side effect.*
If you have questions about when and how much food or drinks you should consume while taking Nocdurna, talk with your doctor. * Nocdurna has a boxed warning for this side effect. This is a serious warning from the Food and Drug Administration (FDA).
thumb_up
42 likes
K
To learn more, see the “Nocdurna precautions” section below. Can Nocdurna be crushed split or chewed
No, Nocdurna is not meant to be crushed, split, chewed, or swallowed whole. Nocdurna comes as a sublingual tablet that you place under your tongue.
thumb_up
5 likes
A
The tablet will completely dissolve under your tongue within seconds. How Nocdurna works
Nocdurna is approved to treat nocturia (frequent urination at night) in adults. Specifically, it’s prescribed to people who wake up at least twice to urinate due to nocturnal polyuria.
thumb_up
32 likes
S
With this condition, your kidneys make too much urine at night. Nocdurna works to reduce the amount of urine your body makes.
thumb_up
21 likes
O
It belongs to a group of drugs called antidiuretics (also called vasopressin analogs) and contains the active ingredient desmopressin acetate. Desmopressin acetate gets absorbed into the body as desmopressin. Desmopressin is an analog (synthetic version) of the hormone vasopressin.
thumb_up
30 likes
Z
Also called an antidiuretic hormone, vasopressin is a natural hormone. It reduces how much urine your body makes.
thumb_up
44 likes
S
Nocturnal polyuria is caused by low levels of vasopressin at night, among other factors. So, to treat this condition, Nocdurna works by mimicking the effects of vasopressin.
thumb_up
35 likes
C
The drug helps the kidneys store water instead of getting rid of it in the urine. This leads to less urine production at night.
thumb_up
15 likes
W
How long does it take to work
Nocdurna starts working within 30 minutes after you take a dose. In clinical trials, most people who took Nocdurna over a 3-month period saw a decrease in the average number of times they had to urinate at night. If you have questions about how Nocdurna works or what to expect from treatment, talk with your doctor or pharmacist.
thumb_up
34 likes
H
Nocdurna and pregnancy
It’s not known for sure if Nocdurna is safe for pregnant people to take. If you’re pregnant, your doctor will likely recommend you do not take Nocdurna. In animal studies, desmopressin acetate, the active ingredient in Nocdurna, did not cause problems with fetal development.
thumb_up
6 likes
S
However, keep in mind that animal studies do not always predict what could happen in humans. Nocturia (frequent urination at night) is very common during pregnancy.* However, doctors will not typically recommend Nocdurna or any other drug to treat nocturia in pregnant people.
thumb_up
11 likes
L
If you’re pregnant and have nocturia, talk with your doctor about other ways to cope with frequent urination at night. * Nocdurna is used to treat nocturia in certain adults.
thumb_up
14 likes
O
For more information, see the “Nocdurna uses” section above. Nocdurna and birth control
It’s not known whether Nocdurna is safe to take during pregnancy.
thumb_up
33 likes
M
If you or your partner could become pregnant, talk with your doctor about your birth control needs while you’re taking Nocdurna. For more information about taking Nocdurna during pregnancy, see the “Nocdurna and pregnancy” section above.
thumb_up
50 likes
K
Nocdurna and breastfeeding
It isn’t known if Nocdurna is safe to take while breastfeeding. Clinical trials of a nasal spray form of desmopressin acetate, the active ingredient in Nocdurna, showed that small amounts of the drug pass into breast milk. So, a breastfed child may be exposed to the drug.
thumb_up
11 likes
W
However, it isn’t known what effects it could have, if any. If you’re breastfeeding or planning to breastfeed, talk with your doctor.
thumb_up
11 likes
S
They’ll help you weigh the advantages and disadvantages of breastfeeding and recommend the best plan for you and your child. Common questions about Nocdurna
Here are answers to some frequently asked questions about Nocdurna.
thumb_up
42 likes
R
Does Nocdurna come in strengths of 25 mcg and 50 mcg
Nocdurna tablets come in two strengths: 27.7 micrograms (mcg) and 55.3 mcg. Each 27.7-mcg tablet of Nocdurna provides 25 mcg of desmopressin.
thumb_up
50 likes
E
And each 55.3-mcg tablet of Nocdurna provides 50 mcg of desmopressin. You may see these amounts written as 0.025 mg and 0.050 mg. (One milligram [mg] is equal to 1,000 mcg.)
Desmopressin is an analog (synthetic version) of a hormone that’s made in your body.
thumb_up
3 likes
E
When you take Nocdurna, your body absorbs Nocdurna’s active ingredient, desmopressin acetate, as desmopressin. (For more details, see the “How Nocdurna works” section above.)
If you have questions about the strengths of Nocdurna that you’re prescribed, talk with your doctor. How does Nocdurna compare with Minirin
Minirin is a brand-name drug that’s no longer available in the United States.
thumb_up
18 likes
G
However, doctors can still prescribe the generic version of this drug called desmopressin acetate nasal spray. It contains the same active ingredient as Nocdurna, desmopressin acetate.
thumb_up
26 likes
I
The drug Minirin Melt is available in other countries, such as Australia. As with Nocdurna, it comes as a sublingual tablet (a tablet that dissolves under your tongue) containing desmopressin acetate.
thumb_up
17 likes
A
Generic versions of this active ingredient are available by prescription in the U.S. (For more information, see the “Nocdurna generic” section above.)
The table below compares some key details about Nocdurna and Minirin:Active ingredient and brand nameUseFormStrengthdesmopressin acetate (Nocdurna)• to treat nocturia due to nocturnal polyuria (frequent urination at night)* • sublingual tablet (tablet that dissolves under your tongue)• 27.7 micrograms (mcg)• 55.3 mcgdesmopressin acetate (formerly Minirin, others)• to treat nocturnal enuresis (bedwetting)• to treat central cranial diabetes insipidus (excessive thirst and urination)• excessive thirst and urination after brain injury or surgery• liquid solution, taken as a nasal spray• 10 mcg per spray (0.1 milliliter [mL] of solution) * For details about this use, see the “Nocdurna uses” section above.
thumb_up
10 likes
S
To learn more about how these drugs compare, talk with your doctor or pharmacist. Can I drink fluids when I take my dose of Nocdurna
No.
thumb_up
43 likes
C
You should avoid drinking fluids for 1 hour before your Nocdurna dose and 8 hours after. Drinking too much water or other fluids can increase the risk of hyponatremia (low blood sodium [salt] level), a serious side effect of Nocdurna.*
You’ll take your Nocdurna tablet 1 hour before bedtime without drinking anything.
thumb_up
19 likes
C
The tablet will quickly dissolve under your tongue without water. (For more information about how to take the drug, see the “How to take Nocdurna” section above.)
You should also avoid drinking alcohol or caffeine close to bedtime.
thumb_up
35 likes
M
These can cause your body to produce more urine than usual. And Nocdurna is meant to reduce the amount of urine you produce. (For more details about alcohol and Nocdurna, see the “Nocdurna and alcohol” section above.
thumb_up
41 likes
K
And to learn more about what Nocdurna is used for, see the “Nocdurna uses” section above.)
If you have questions about the type and amount of liquids to drink while taking Nocdurna, talk with your doctor. * Nocdurna has a boxed warning for this side effect. This is a serious warning from the Food and Drug Administration (FDA).
thumb_up
0 likes
E
To learn more, see the “Nocdurna precautions” section below. Why is the dose of Nocdurna different for males and females
The recommended dose of Nocdurna for males* is 55.3 micrograms (mcg), and for females*, it’s 27.7 mcg. The dose for females is lower because females were more sensitive to Nocdurna’s effects in the drug’s clinical trials.
thumb_up
30 likes
N
In these trials, females who took 55.3 mcg had an increased risk of hyponatremia, a serious side effect of the drug.†
Talk with your doctor if you have questions about your dosage or the risk of Nocdurna’s side effects. For more information about the side effects of the drug, see the “Nocdurna side effects” section above. * Sex and gender exist on spectrums.
thumb_up
24 likes
E
Use of the terms “male” and “female” in this article refers to sex assigned at birth. † Nocdurna has a boxed warning for this side effect. This is a serious warning from the Food and Drug Administration (FDA).
thumb_up
45 likes
N
To learn more, see the “Nocdurna precautions” section below. Nocdurna precautions
This drug comes with several precautions. These are considered drug-condition interactions.
thumb_up
37 likes
S
FDA warning Hyponatremia
This drug has a boxed warning about the risk of hyponatremia. This is a serious warning from the Food and Drug Administration (FDA).
thumb_up
18 likes
S
A boxed warning alerts doctors and patients about drug effects that may be dangerous. Nocdurna may cause hyponatremia (low blood sodium [salt] level).
thumb_up
27 likes
E
This side effect may be mild to severe. In clinical trials, hyponatremia was a common side effect of Nocdurna. In fact, it was the most common reason why people had to stop taking the drug.
thumb_up
45 likes
N
However, cases of severe hyponatremia were rare in the drug’s clinical trials. Severe hyponatremia that isn’t treated could lead to seizures, coma, or respiratory arrest (when breathing stops). It could even be life threatening in rare cases.
thumb_up
45 likes
C
Seek immediate medical care if you take Nocdurna and have the following symptoms of hyponatremia:dizzinessfatigueconfusionnauseavomitingmuscle cramps
Before prescribing Nocdurna, your doctor will check your sodium level with a blood test. And they’ll recheck it throughout your Nocdurna treatment.
thumb_up
34 likes
W
This includes 1 week and 1 month after you start treatment. If your sodium level falls below the usual range, your doctor will likely have you pause or stop Nocdurna treatment. Be sure to get blood tests recommended by your doctor.
thumb_up
35 likes
I
Older adults (ages 65 years or older) and people with certain conditions may need more frequent monitoring. Doctors typically will not prescribe Nocdurna to people who have certain factors that increase the risk of hyponatremia.
thumb_up
35 likes
C
These are listed in the “Contraindications” section below. Contraindications
Nocdurna has several contraindications related to the boxed warning described above.
thumb_up
36 likes
A
Contraindications are factors or conditions that may prevent your doctor from prescribing a drug due to the risk of harm. Doctors typically will not prescribe Nocdurna to people with certain factors that increase the risk of hyponatremia.
thumb_up
48 likes
V
These factors include:current or past hyponatremiapolydipsia (intense thirst despite drinking plenty of fluids)current use of certain diuretic or glucocorticoids (for more details, see the “Nocdurna interactions” section above)reduced kidney functionsyndrome of inappropriate antidiuretic hormone (a condition that makes it hard for your body to release water)illnesses that may cause electrolyte or fluid imbalances, such as kidney problems or gastroenteritis
Talk with your doctor if you have questions about the risk of hyponatremia. Other precautions
Before taking Nocdurna, talk with your doctor about your health history.
thumb_up
4 likes
N
Nocdurna may not be right for you if you have certain medical conditions or other factors affecting your health. These include:Medical conditions worsened by fluid buildup.
thumb_up
42 likes
M
Nocdurna may cause fluid buildup as a side effect. This may make symptoms of certain medical conditions more severe. So, your doctor typically will not prescribe Nocdurna if you have heart failure or high blood pressure that isn’t well-managed.
thumb_up
25 likes
A
Also, they may not prescribe the drug if you have urinary retention or have an increased risk of intracranial pressure.Allergic reaction. If you’ve had an allergic reaction to Nocdurna or any of its ingredients, your doctor will likely not prescribe this drug.
thumb_up
6 likes
K
Ask your doctor about other medications that may be better options for you.Pregnancy. It isn’t known for sure if Nocdurna is safe for use during pregnancy. The drug isn’t recommended to treat nocturia in pregnant people.
thumb_up
45 likes
E
For more information, see the “Nocdurna and pregnancy” section above.Breastfeeding. It isn’t known if Nocdurna is safe to take while breastfeeding a child.
thumb_up
7 likes
L
For more information, see the “Nocdurna and breastfeeding” section above. Note: For more information about the potential negative effects of Nocdurna, see the “Nocdurna side effects” section above.
thumb_up
14 likes
N
Nocdurna overdose
Taking more than the recommended dosage of Nocdurna can lead to serious side effects. Do not take more Nocdurna than your doctor recommends. (For information on the recommended dosages of Nocdurna, see the “Nocdurna dosage” section above.)
Overdose symptoms
Signs and symptoms of an overdose of Nocdurna may include:fluid buildup, which may cause rapid weight gainnauseaheadachedrowsinessconfusionhyponatremia (low blood sodium [salt] level)* * Nocdurna has a boxed warning for this side effect.
thumb_up
0 likes
E
This is a serious warning from the Food and Drug Administration (FDA). To learn more, see the “Nocdurna precautions” section above. What to do in case of overdose
If you think you’ve taken too much of this drug, call your doctor.
thumb_up
8 likes
W
You can also call the American Association of Poison Control Centers at 800-222-1222 or use its online tool. However, if your symptoms are severe, call 911 or your local emergency number, or go to the nearest emergency room right away.
thumb_up
29 likes
G
Nocdurna expiration storage and disposal
When you get Nocdurna from the pharmacy, the pharmacist will add an expiration date to the label on the packaging. This date is typically 1 year from the date they dispensed the medication. The expiration date helps guarantee that the medication is effective during this time.
thumb_up
19 likes
J
The current stance of the Food and Drug Administration (FDA) is to avoid using expired medications. If you have unused medication that has passed the expiration date, talk with your pharmacist about whether you might still be able to use it.
thumb_up
10 likes
J
Storage
How long a medication remains good to use can depend on many factors, including how and where you store the medication. Nocdurna tablets come in blister packs. With these packs, you’ll push the tablet through to take your dose.
thumb_up
25 likes
L
Keep the medication sealed in these packs until you’re about to take a dose. Store Nocdurna at a room temperature of 68°F to 77°F (20°C to 25°C), away from light. The drug may be stored between 59°F and 86°F (15°C and 30°C) for short periods of time.
thumb_up
45 likes
J
Avoid storing Nocdurna in areas where it could get damp or wet, such as bathrooms. Disposal
If you no longer need to take Nocdurna and have leftover medication, it’s important to dispose of it safely.
thumb_up
1 likes
A
This helps prevent others, including children and pets, from taking the drug by accident. It also helps keep the drug from harming the environment.
thumb_up
13 likes
D
This article provides several useful tips on medication disposal. You can also ask your pharmacist for information about how to dispose of your medication. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date.
thumb_up
46 likes
T
However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication.
thumb_up
38 likes
A
The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.Overactive Bladder (OAB)Pharmacy / PharmacistUrology / NephrologyDrugsMedically reviewed by Melissa Badowski, PharmD, MPH, FCCP — By Patricia Weiser, PharmD on August 22, 2022
Latest newsWhat sets 'SuperAgers' apart?
thumb_up
31 likes
I
Their unusually large neuronsOmega-3 may provide a brain boost for people in midlifeSeasonal affective disorder (SAD): How to beat it this fall and winterCDC: Monkeypox in the US 'unlikely to be eliminated in the near future'Why are more women prone to Alzheimer's? New clues arise
Related CoverageWhat happens if you drink too much water?Medically reviewed by Adrienne Seitz, MS, RD, LDN
Drinking too much water can lead to water intoxication, which can be fatal.
thumb_up
16 likes
E
However, this is rare. Learn about the symptoms, causes, and risk factors…READ MOREHaving trouble sleeping: What to knowMedically reviewed by Deborah Weatherspoon, Ph.D., MSN
Sleeping difficulties can negatively impact a person’s health. Read this article to learn about the causes and treatment options available.READ MOREUrinary incontinence: What you need to knowMedically reviewed by University of Illinois
Urinary incontinence is sometimes known as leaky bladder.
thumb_up
3 likes
N
It means that a person cannot prevent urine from leaking out. It is more frequent in women…READ MOREIs urine leakage while coughing normal?Medically reviewed by Daniel Murrell, MD
When some people cough, it can lead to a leakage of urine.
thumb_up
5 likes
A
Experiencing urine leakage when coughing is relatively common, especially in women, but is…READ MOREFoods for bladder healthMedically reviewed by Natalie Olsen, R.D., L.D., ACSM EP-C
Having an overactive bladder can be a very challenging condition, but there are many ways in which people can improve their symptoms. These include…READ MORE
thumb_up
7 likes
Similar Discussions
-
5 best powerful cards for the latest Sudden Death challenge in Clash Royale
-
Vince McMahon wanted to stomp on AEW according to former WWE Superstar
-
Fans breakdown into multiple chants as Rhea Ripley and Dominik Mysterio walk out
-
NOR vs KHP Dream11 Prediction Fantasy Cricket Tips Today s Playing 11 Player Stats and Pitch Report for National T20 Cup 2022 Match 6
-
Deleted Media File Recovery APK Download for Android APKfun com
-
サイコボーイ 脱出ゲーム APK Download for Android
-
First Baptist Church Canton APK Download for Android
-
wheather live APK Download for Android
-
Talking Dancing Ganesha APK Download for Android
-
pingl pour ses fastueux d ners Laurent Wauquiez pense qu il g ne
-
R sultat et r sum France F Angleterre F match en direct Coupe du monde F 2022 2e journ e Poule C samedi 15 octobre 2022 Fraang
-
Tamara Falc explica su pol mica opini n sobre la sexualidad Me refer a a las desviaciones de mi ex Tamara Falco
-
Dragon Ball La fusi n con Aros Pothala entre Goku y Vegeta en Super Saiyajin 4 c mo nunca la hab as visto Dragon Ball Super Saiyajin 4
-
30 Smells People Willingly Admit They Love As Shared In This Online Thread
-
10 last minute fashion deals to nab before Prime Day 2021 ends
-
It s semi official Men are stupider than women
-
Unique Selling Proposition What Is a USP and Why It s Important
-
10 Best Online Checking Accounts NerdWallet
-
Edit Tweet rollout begins for Twitter Blue subscribers Digital Trends
-
North Korean hackers offer fake jobs to distribute malware Digital Trends
-
The 9 Best SATA Hard Drives Tested by Lifewire
-
Compare Ferrari F430 vs Porsche 911 GT2 RS CarBuzz
-
Compare Infiniti QX60 Hybrid vs Lincoln MKX CarBuzz
-
McLaren Speedtail Bespoke Badges Are Fine Jewelry For Your Car Not Your Wife CarBuzz
-
甲亢 医生与科室 妙佑医疗国际
-
Recetas de postres saludables Mayo Clinic
-
He Hurt Me So Much But I Still Love Him
-
Dt466 Cranks But Wont Start
-
How To Replace Windshield Wipers Gmc Sierra
-
Lincoln Town Car Problems