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%Start New Organ-Chip Can Re-Create Intestinal Cells  Cedars-Sinai Skip to content Close 
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 New Organ-Chip Can Re-Create the Cells of Your Intestines Apr 04, 2018 Cedars-Sinai Staff Share Tweet Post Cells of a human intestinal lining, after being placed in an Intestine-Chip, form intestinal folds as they do in the human body. Photo: Cedars-Sinai Board of Governors Regenerative Medicine Institute.
%Start New Organ-Chip Can Re-Create Intestinal Cells Cedars-Sinai Skip to content Close Select your preferred language English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog Menu Close Call 1-800-CEDARS-1 toggle search form Close Share Email Print CS-Blog Cedars-Sinai Blog New Organ-Chip Can Re-Create the Cells of Your Intestines Apr 04, 2018 Cedars-Sinai Staff Share Tweet Post Cells of a human intestinal lining, after being placed in an Intestine-Chip, form intestinal folds as they do in the human body. Photo: Cedars-Sinai Board of Governors Regenerative Medicine Institute.
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Researchers at the Cedars-Sinai Board of Governors Regenerative Medicine Institute have teamed up with Emulate Inc. to potentially change how patients are treated for debilitating, inflammatory gastrointestinal diseases such as Crohn's disease, ulcerative colitis, and irritable bowel syndrome. The project is part of the Cedars-Sinai Precision Health initiative to drive the development of new technology and research that enables personalized healthcare.
Researchers at the Cedars-Sinai Board of Governors Regenerative Medicine Institute have teamed up with Emulate Inc. to potentially change how patients are treated for debilitating, inflammatory gastrointestinal diseases such as Crohn's disease, ulcerative colitis, and irritable bowel syndrome. The project is part of the Cedars-Sinai Precision Health initiative to drive the development of new technology and research that enables personalized healthcare.
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Audrey Mueller 3 minutes ago
Researchers have already reproduced normal human intestine cells on an Organ-Chip outside the body. ...
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Lily Watson 4 minutes ago
Why it matters Instead of exposing a patient to drug treatments that may be ineffective or carry har...
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Researchers have already reproduced normal human intestine cells on an Organ-Chip outside the body. In the future, they hope to reproduce the intestine cells of specific patients and then test potential treatments on the chip.
Researchers have already reproduced normal human intestine cells on an Organ-Chip outside the body. In the future, they hope to reproduce the intestine cells of specific patients and then test potential treatments on the chip.
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Audrey Mueller 2 minutes ago
Why it matters Instead of exposing a patient to drug treatments that may be ineffective or carry har...
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Christopher Lee 9 minutes ago
"This pairing of biology and engineering allows us to re-create an intestinal lining that m...
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Why it matters Instead of exposing a patient to drug treatments that may be ineffective or carry harmful side effects, or risk infection with surgical procedures, the Intestine-Chip could allow researchers to find the best personalized treatment outside of the body. The chips potentially could also be used for testing food-related inflammation to get a more complete picture of a patient's intestinal health and food sensitivities.
Why it matters Instead of exposing a patient to drug treatments that may be ineffective or carry harmful side effects, or risk infection with surgical procedures, the Intestine-Chip could allow researchers to find the best personalized treatment outside of the body. The chips potentially could also be used for testing food-related inflammation to get a more complete picture of a patient's intestinal health and food sensitivities.
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Audrey Mueller 14 minutes ago
"This pairing of biology and engineering allows us to re-create an intestinal lining that m...
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Mia Anderson 2 minutes ago
How it works Cedars-Sinai investigators take small samples of blood and skin cells from donors. Thes...
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"This pairing of biology and engineering allows us to re-create an intestinal lining that matches that of a patient with a specific intestinal disease—without performing invasive surgery to obtain a tissue sample," says Clive Svendsen, PhD, director of the Cedars-Sinai Board of Governors Regenerative Medicine Institute, which is conducting the research with Emulate Inc. "We can produce an unlimited number of copies of this tissue and use them to evaluate potential therapies." Microengineered Organ-Chip, made out of a flexible polymer, features tiny channels that can be lined with thousands of living human cells. Photo: Emulate, Inc.
"This pairing of biology and engineering allows us to re-create an intestinal lining that matches that of a patient with a specific intestinal disease—without performing invasive surgery to obtain a tissue sample," says Clive Svendsen, PhD, director of the Cedars-Sinai Board of Governors Regenerative Medicine Institute, which is conducting the research with Emulate Inc. "We can produce an unlimited number of copies of this tissue and use them to evaluate potential therapies." Microengineered Organ-Chip, made out of a flexible polymer, features tiny channels that can be lined with thousands of living human cells. Photo: Emulate, Inc.
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Aria Nguyen 16 minutes ago
How it works Cedars-Sinai investigators take small samples of blood and skin cells from donors. Thes...
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Andrew Wilson 14 minutes ago
From there, they use these cells to replicate the intestinal lining cells of the donor. These new ce...
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How it works Cedars-Sinai investigators take small samples of blood and skin cells from donors. These cells are genetically manipulated into induced pluripotent stem cells (iPSCs), which are similar to embryonic stem cells and can produce any type of body cell.
How it works Cedars-Sinai investigators take small samples of blood and skin cells from donors. These cells are genetically manipulated into induced pluripotent stem cells (iPSCs), which are similar to embryonic stem cells and can produce any type of body cell.
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Sebastian Silva 2 minutes ago
From there, they use these cells to replicate the intestinal lining cells of the donor. These new ce...
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Zoe Mueller 7 minutes ago
Tags Crohn's Disease Gastroenterology Gut Health Research IBS Share Tweet Post Popular C...
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From there, they use these cells to replicate the intestinal lining cells of the donor. These new cells are used to grow miniature versions of the person's intestinal lining, known as organoids. Cells from the organoids are placed on Intestine-Chips, which re-create the natural environment of the human intestine and allow the cells to interact with immune cells, blood cells, and drugs.
From there, they use these cells to replicate the intestinal lining cells of the donor. These new cells are used to grow miniature versions of the person's intestinal lining, known as organoids. Cells from the organoids are placed on Intestine-Chips, which re-create the natural environment of the human intestine and allow the cells to interact with immune cells, blood cells, and drugs.
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Tags Crohn's Disease Gastroenterology Gut Health Research IBS Share Tweet Post Popular Categories Health + Wellness Science + Innovation Community Blog &amp Magazines catalyst Blog &amp Magazines Home CS-Blog Blog CS Magazine Cedars-Sinai Magazine discoveries magazine Discoveries Magazine Embracing our Community Embracing Our Community Blog &amp Magazines catalyst Blog &amp Magazines Home CS-Blog Blog Embracing our Community Embracing Our Community CS Magazine Cedars-Sinai Magazine discoveries magazine Discoveries Magazine Popular Topics Research Innovation Technology Clinical Trials Healthcare Accelerator Make an Appointment Find a Doctor Schedule a Callback Call us 24 hours a day 1-800-CEDARS-1 Support Cedars-Sinai Make a Gift Volunteer Share Email Print Please ensure Javascript is enabled for purposes of website accessibility
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Brandon Kumar 1 minutes ago
New Organ-Chip Can Re-Create Intestinal Cells Cedars-Sinai Skip to content Close Select your pref...

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