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 Select your preferred language English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog Menu Close Call 1-800-CEDARS-1 toggle search form Close 15 October 2013  23:49 PM America/Los_Angeles 
 New Blood Test Could Help Millions of Patients with Gastrointestinal Disorders 
 Study identifies test for high levels of vinculin antibodies in patients with irritable bowel syndrome  IBS 
Los Angeles - Oct. 15, 2013 – For the first time, a simple blood test may be the best way to determine if a patient is suffering from Irritable Bowel Syndrome (IBS), or another serious condition such as Inflammatory Bowel Disease (IBD), according to Cedars-Sinai physician researcher Mark Pimentel, MD, lead author of a multicenter clinical trial
Researchers conclusively identified a test for antibodies that form against a particular protein, vinculin, found in the guts of patients, many of whom suffered acute gastroenteritis at some point.
New Blood Test Could Help Millions of Patients with Gastrointestinal Disorders Skip to main content Close Select your preferred language English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog Menu Close Call 1-800-CEDARS-1 toggle search form Close 15 October 2013 23:49 PM America/Los_Angeles New Blood Test Could Help Millions of Patients with Gastrointestinal Disorders Study identifies test for high levels of vinculin antibodies in patients with irritable bowel syndrome IBS Los Angeles - Oct. 15, 2013 – For the first time, a simple blood test may be the best way to determine if a patient is suffering from Irritable Bowel Syndrome (IBS), or another serious condition such as Inflammatory Bowel Disease (IBD), according to Cedars-Sinai physician researcher Mark Pimentel, MD, lead author of a multicenter clinical trial Researchers conclusively identified a test for antibodies that form against a particular protein, vinculin, found in the guts of patients, many of whom suffered acute gastroenteritis at some point.
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Victoria Lopez 4 minutes ago
"This is a major breakthrough. It is the first test with a high specificity for IBS, likely...
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"This is a major breakthrough. It is the first test with a high specificity for IBS, likely based on a pathological mechanism of the disease," said Pimentel, the director of the Cedars-Sinai GI Motility Program and the GI Motility Laboratory.
"This is a major breakthrough. It is the first test with a high specificity for IBS, likely based on a pathological mechanism of the disease," said Pimentel, the director of the Cedars-Sinai GI Motility Program and the GI Motility Laboratory.
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Pimentel is co-author of the study and results were presented for the first time this week at the American College of Gastroenterology's 78th Annual Scientific Meeting in San Diego, Calif. In the study, 221 patients were evaluated; some had a diagnosis of IBS, some were diagnosed with IBD and some were healthy, with no symptoms.
Pimentel is co-author of the study and results were presented for the first time this week at the American College of Gastroenterology's 78th Annual Scientific Meeting in San Diego, Calif. In the study, 221 patients were evaluated; some had a diagnosis of IBS, some were diagnosed with IBD and some were healthy, with no symptoms.
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Anti-vinculin antibodies were significantly elevated in IBS patients as compared to those with IBD or those who were healthy. "Until this study, there had been no accurate biomarkers identified specifically for IBS.
Anti-vinculin antibodies were significantly elevated in IBS patients as compared to those with IBD or those who were healthy. "Until this study, there had been no accurate biomarkers identified specifically for IBS.
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Ryan Garcia 4 minutes ago
The new blood test has the potential to distinguish IBS from IBD and reduce the need for unnecessary...
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Dylan Patel 9 minutes ago
But millions of patients are never diagnosed correctly. A simple blood test at the first sign of sym...
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The new blood test has the potential to distinguish IBS from IBD and reduce the need for unnecessary testing, expense and years of suffering," says Pimentel. Irritable Bowel Syndrome is the most common gastrointestinal disorder in the U.S., afflicting 30 million people. Food poisoning has been identified as a significant risk factor for developing the disorder which is characterized by a cluster of symptoms including diarrhea, bloating and abdominal pain.
The new blood test has the potential to distinguish IBS from IBD and reduce the need for unnecessary testing, expense and years of suffering," says Pimentel. Irritable Bowel Syndrome is the most common gastrointestinal disorder in the U.S., afflicting 30 million people. Food poisoning has been identified as a significant risk factor for developing the disorder which is characterized by a cluster of symptoms including diarrhea, bloating and abdominal pain.
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Andrew Wilson 17 minutes ago
But millions of patients are never diagnosed correctly. A simple blood test at the first sign of sym...
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Julia Zhang 18 minutes ago
Today, antibiotics play a key therapeutic role in bringing relief to millions of patients. A definit...
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But millions of patients are never diagnosed correctly. A simple blood test at the first sign of symptoms means patients who have IBS could get effective treatment sooner. More than a decade ago, Pimentel went up against the conventional medical understanding of IBS when his research suggested the overgrowth of bacteria in the gut was a contributing cause of the condition.
But millions of patients are never diagnosed correctly. A simple blood test at the first sign of symptoms means patients who have IBS could get effective treatment sooner. More than a decade ago, Pimentel went up against the conventional medical understanding of IBS when his research suggested the overgrowth of bacteria in the gut was a contributing cause of the condition.
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Today, antibiotics play a key therapeutic role in bringing relief to millions of patients. A definitive blood test for IBS would represent a significant new development. The study was performed in collaboration with physician scientists at Beth Israel Deaconess Medical GAS in Boston.
Today, antibiotics play a key therapeutic role in bringing relief to millions of patients. A definitive blood test for IBS would represent a significant new development. The study was performed in collaboration with physician scientists at Beth Israel Deaconess Medical GAS in Boston.
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Isabella Johnson 11 minutes ago
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"This is a major breakthrough. It is the first test with a high specificity for IBS, likely...

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