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Can Gut Health Affect Multiple Sclerosis
Researchers are still investigating the relationship between the gut microbiome and MS, but here’s what we know so far. By Kerry WeissMedically Reviewed by Jason Paul Chua, MD, PhDReviewed: June 14, 2022Medically ReviewedRebalancing your gut microbiome may have an impact on your MS.Zhanna Mendel/ShutterstockTrillions of bacteria, fungi, and other organisms live in your digestive system. Collectively known as your gut microbiome, normally these microbes coexist peacefully, working together to support digestion, immunity, and overall health.
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Daniel Kumar 2 minutes ago
However, if something such as a dramatic change in diet occurs, it can throw off the balance of the ...
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The Link Between Gut Health and MS
The relationship between the gut and MS is complex, acco...
However, if something such as a dramatic change in diet occurs, it can throw off the balance of the gut microbiome and affect your health, putting you at risk of developing certain diseases — among them, multiple sclerosis (MS). Studies have consistently found people with MS to have markedly different gut microbiomes from those who don’t have the disease, although what this means for people living with MS isn’t fully understood. Here’s what researchers do know.
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Brandon Kumar Member
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The Link Between Gut Health and MS
The relationship between the gut and MS is complex, according to J. William Lindsey, MD, director of the division of multiple sclerosis and neuroimmunology at the University of Texas Health Science Center at Houston. “It involves interactions between diet, nutritional status, the bacteria in the gut, and the activity of the immune system,” he explains.
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Mia Anderson 6 minutes ago
How does all this intertwine? For starters, “diet affects nutritional status, and it also changes ...
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Lindsey. This disruption in the gut bacteria can set off a chain reaction. “The microbiome can aff...
How does all this intertwine? For starters, “diet affects nutritional status, and it also changes the composition and activity of the bacteria in the gut microbiome,” says Dr.
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Lindsey. This disruption in the gut bacteria can set off a chain reaction. “The microbiome can aff...
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Lindsey. This disruption in the gut bacteria can set off a chain reaction. “The microbiome can affect the activity of the white blood cells in the intestine, and these white blood cells can migrate to other parts of the body, including the brain,” explains Lindsey. “The microbiome also produces metabolites such as short chain fatty acids and altered bile acids that get into the blood and affect immune system activity.”
Because MS is an autoimmune disease of the central nervous system, these disruptions, which lead to an increase in pro-inflammatory bacteria in the gut, are thought to impact the condition.
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Can Modifying Bacteria in the Gut Change the Course of MS
Maintaining a consistently healt...
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Ryan Garcia 4 minutes ago
However, these aren’t definitive studies — more research consisting of larger studies is needed ...
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Ryan Garcia Member
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Can Modifying Bacteria in the Gut Change the Course of MS
Maintaining a consistently healthy diet can impact the gut microbiome. And findings from various small studies done both in people and in mice suggest a healthy diet can reduce MS disease activity, especially in combination with disease-modifying therapy and other healthy lifestyle habits.
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Liam Wilson 15 minutes ago
However, these aren’t definitive studies — more research consisting of larger studies is needed ...
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Charlotte Lee 14 minutes ago
That said, studies are limited by a focus on MS outcomes, and there aren’t many analyses specifica...
However, these aren’t definitive studies — more research consisting of larger studies is needed to help clarify the role diet plays in modifying the gut microbiome and managing MS.
MS-Friendly Diet Tips to Promote Gut Health
Regardless of what we know — and still don’t know — about the link between the gut microbiome and MS, research has shown that taking steps to eat a healthy diet is considered an important part of an overall MS management plan. “And a healthy diet can lead to a healthier microbiome,” adds Lindsey.
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Ryan Garcia Member
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That said, studies are limited by a focus on MS outcomes, and there aren’t many analyses specifically looking at microbiome composition in response to diet. While there are no dietary guidelines specific to MS, the same eating plans known to support cardiovascular health and promote healthy aging — such as the DASH and Mediterranean diets — are also good for MS, explains Lindsey.
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Dylan Patel 24 minutes ago
That means eating a diet focused on:FruitsVegetablesWhole grainsLegumesNutsSeedsHealthy fats
And lim...
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Natalie Lopez 3 minutes ago
Unmanaged inflammation is what triggers the overactive immune response. Studies have shown that cons...
That means eating a diet focused on:FruitsVegetablesWhole grainsLegumesNutsSeedsHealthy fats
And limiting:Processed foodsAdded sugarsRefined grains
Can Probiotics Help
The terms “gut health” and “probiotics” often go hand in hand. That’s because increasing your intake of probiotics, or “good” bacteria, can help reduce inflammation in your gut.
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Isaac Schmidt Member
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Unmanaged inflammation is what triggers the overactive immune response. Studies have shown that consuming probiotics may help prevent MS to begin with. And for people who develop MS, probiotics may help reduce its severity, delay progression, and improve certain MS symptoms.
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Ethan Thomas Member
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Tuesday, 06 May 2025
Though larger, more comprehensive research is needed on this topic as well. Probiotics can be found in fermented foods such as:KefirKimchiKombuchaMisoPicklesSauerkrautTempehYogurt
Probiotics also come in the form of supplements for people who don’t care for the signature sour, yeasty flavor of food sources.
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Jack Thompson Member
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Tuesday, 06 May 2025
That said, only certain strains of Lactobacillus and Bifidobacterium have been proven to be beneficial for MS. It’s important to note probiotic supplements are not regulated by the U.S.
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Audrey Mueller 41 minutes ago
Food and Drug Administration, so before you stock up, check with your doctor. Given the link between...
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Sebastian Silva 16 minutes ago
That said, it’s probably fine to dine on all the kimchi and yogurt you like.
Food and Drug Administration, so before you stock up, check with your doctor. Given the link between the gut microbiome and MS isn’t yet fully understood, it’s best to err on the side of caution.
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William Brown 1 minutes ago
That said, it’s probably fine to dine on all the kimchi and yogurt you like.
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