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%Start Liver Conditions in Children Johns Hopkins Medicine COVID-19 Updates Masks are required inside all of our care facilities. We are vaccinating all eligible patients. Learn more: Vaccines, Boosters & Additional Doses Testing Patient Care Visitor Guidelines Coronavirus Email Alerts Find more COVID-19 testing locations on Maryland.gov.
Audrey Mueller Member
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%Start Liver Conditions in Children Johns Hopkins Medicine COVID-19 Updates Masks are required inside all of our care facilities. We are vaccinating all eligible patients. Learn more: Vaccines, Boosters & Additional Doses Testing Patient Care Visitor Guidelines Coronavirus Email Alerts Find more COVID-19 testing locations on Maryland.gov.
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Charlotte Lee 3 minutes ago
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CloseSearch Submit Search Popular Searches coronavirus careers medical records map insurance accepted telemedicine Menu Health Liver Conditions in Children Share on Facebook Share on Twitter Share on Linkedin Share on Pinterest Share via Email Print this Page Acute Liver Failure This alarming syndrome usually occurs in a previously well infant, child or adolescent and can be caused by a number of infectious or metabolic causes and reactions to medication. Jaundice occurs rapidly, often in concert with gastrointestinal symptoms like vomiting and fever.
Emma Wilson Admin
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CloseSearch Submit Search Popular Searches coronavirus careers medical records map insurance accepted telemedicine Menu Health Liver Conditions in Children Share on Facebook Share on Twitter Share on Linkedin Share on Pinterest Share via Email Print this Page Acute Liver Failure This alarming syndrome usually occurs in a previously well infant, child or adolescent and can be caused by a number of infectious or metabolic causes and reactions to medication. Jaundice occurs rapidly, often in concert with gastrointestinal symptoms like vomiting and fever.
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Scarlett Brown 2 minutes ago
We are committed to serving children with this disorder as soon as we are notified and work with our...
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Charlotte Lee 4 minutes ago
This causes a deficiency of the A1AT protein in the circulation. A1AT is a specialized protein that ...
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We are committed to serving children with this disorder as soon as we are notified and work with our emergency transport team, intensive care specialists and if necessary, our pediatric liver surgeons to provide 24-hour care for the best outcome possible for children with this condition. What is alpha-1 antitrypsin deficiency Alpha-1 antitrypsin (A1AT) deficiency is an inherited disease in which a protein known as A1AT is unable to be released from the liver into the blood in adequate amounts.
Joseph Kim Member
access_time 15 minutes ago
We are committed to serving children with this disorder as soon as we are notified and work with our emergency transport team, intensive care specialists and if necessary, our pediatric liver surgeons to provide 24-hour care for the best outcome possible for children with this condition. What is alpha-1 antitrypsin deficiency Alpha-1 antitrypsin (A1AT) deficiency is an inherited disease in which a protein known as A1AT is unable to be released from the liver into the blood in adequate amounts.
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This causes a deficiency of the A1AT protein in the circulation. A1AT is a specialized protein that blocks the action of other proteins important in inflammation (swelling) and breakdown of tissues in the body.
Liam Wilson Member
access_time 8 minutes ago
This causes a deficiency of the A1AT protein in the circulation. A1AT is a specialized protein that blocks the action of other proteins important in inflammation (swelling) and breakdown of tissues in the body.
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When the A1AT protein is deficient in the circulation, tissue inflammation and tissue damage is more severe, especially in the lungs. The defective A1AT protein that remains in the liver may cause liver inflammation (hepatitis) that can progress to cirrhosis (permanent liver scarring) and liver failure.
Sofia Garcia Member
access_time 10 minutes ago
When the A1AT protein is deficient in the circulation, tissue inflammation and tissue damage is more severe, especially in the lungs. The defective A1AT protein that remains in the liver may cause liver inflammation (hepatitis) that can progress to cirrhosis (permanent liver scarring) and liver failure.
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David Cohen 8 minutes ago
A1AT deficiency is quite common, with about 1 in 1,500 to 2,000 people affected. Both parents must b...
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Madison Singh 7 minutes ago
Although carrier parents partially produce the abnormal A1AT protein, they usually have no - or very...
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A1AT deficiency is quite common, with about 1 in 1,500 to 2,000 people affected. Both parents must be carriers of the genetic defect to have a child with A1AT deficiency.
Grace Liu Member
access_time 24 minutes ago
A1AT deficiency is quite common, with about 1 in 1,500 to 2,000 people affected. Both parents must be carriers of the genetic defect to have a child with A1AT deficiency.
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Luna Park 12 minutes ago
Although carrier parents partially produce the abnormal A1AT protein, they usually have no - or very...
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Although carrier parents partially produce the abnormal A1AT protein, they usually have no - or very minimal - symptoms and they may not realize they are partially affected until their child is diagnosed with the condition. Symptoms About 10 percent of newborns with liver disease will be diagnosed with A1AT deficiency.
Ryan Garcia Member
access_time 21 minutes ago
Although carrier parents partially produce the abnormal A1AT protein, they usually have no - or very minimal - symptoms and they may not realize they are partially affected until their child is diagnosed with the condition. Symptoms About 10 percent of newborns with liver disease will be diagnosed with A1AT deficiency.
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Isabella Johnson 3 minutes ago
Newborns may develop jaundice as part of inflammation of the liver associated with A1AT deficiency. ...
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William Brown 18 minutes ago
Adults with A1AT deficiency may have difficulties with chronic obstructive pulmonary disease (COPD),...
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Newborns may develop jaundice as part of inflammation of the liver associated with A1AT deficiency. Older children and teens can present with a liver that has been inflamed for a long time, causing scarring (cirrhosis) to develop. Lung disease usually develops only in adulthood.
Christopher Lee Member
access_time 32 minutes ago
Newborns may develop jaundice as part of inflammation of the liver associated with A1AT deficiency. Older children and teens can present with a liver that has been inflamed for a long time, causing scarring (cirrhosis) to develop. Lung disease usually develops only in adulthood.
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Adults with A1AT deficiency may have difficulties with chronic obstructive pulmonary disease (COPD), emphysema, chronic bronchitis, asthma, coughing and repeated lung infections. Diagnosis Testing is usually done when a child has liver inflammation of uncertain cause or when a family history suggests A1AT liver disease.
Evelyn Zhang Member
access_time 18 minutes ago
Adults with A1AT deficiency may have difficulties with chronic obstructive pulmonary disease (COPD), emphysema, chronic bronchitis, asthma, coughing and repeated lung infections. Diagnosis Testing is usually done when a child has liver inflammation of uncertain cause or when a family history suggests A1AT liver disease.
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Nathan Chen 5 minutes ago
The standard screening test is to measure the amount of A1AT protein in the circulation. In cases of...
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The standard screening test is to measure the amount of A1AT protein in the circulation. In cases of A1AT deficiency, the serum A1AT level will be low. When a low A1AT level is found, an additional test is usually done to identify the types of abnormal A1AT proteins that are in the circulation.
Sophia Chen Member
access_time 40 minutes ago
The standard screening test is to measure the amount of A1AT protein in the circulation. In cases of A1AT deficiency, the serum A1AT level will be low. When a low A1AT level is found, an additional test is usually done to identify the types of abnormal A1AT proteins that are in the circulation.
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Scarlett Brown 7 minutes ago
In rare cases, a more detailed analysis of the DNA in the gene may be necessary. The amount of liver...
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Sophie Martin 32 minutes ago
Therapy involves controlling symptoms and attempting to prevent the development of complications. To...
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In rare cases, a more detailed analysis of the DNA in the gene may be necessary. The amount of liver swelling and damage can be assessed by ultrasonography (sonogram) of the abdomen, blood tests of liver inflammation and function and a liver biopsy, where a small piece of liver tissue is obtained and then examined under the microscope to search for changes typical of A1AT deficiency. Treatment There is no cure for A1AT deficiency.
Emma Wilson Admin
access_time 55 minutes ago
In rare cases, a more detailed analysis of the DNA in the gene may be necessary. The amount of liver swelling and damage can be assessed by ultrasonography (sonogram) of the abdomen, blood tests of liver inflammation and function and a liver biopsy, where a small piece of liver tissue is obtained and then examined under the microscope to search for changes typical of A1AT deficiency. Treatment There is no cure for A1AT deficiency.
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Zoe Mueller 35 minutes ago
Therapy involves controlling symptoms and attempting to prevent the development of complications. To...
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Zoe Mueller 50 minutes ago
It is difficult to predict how severely a liver will be affected. Liver function tests are followed ...
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Therapy involves controlling symptoms and attempting to prevent the development of complications. To protect their lungs, it is very important that the affected person and those around them not smoke. Vaccinations to protect against viruses, such as hepatitis A and hepatitis B, that can further damage the liver should be given.
Natalie Lopez Member
access_time 60 minutes ago
Therapy involves controlling symptoms and attempting to prevent the development of complications. To protect their lungs, it is very important that the affected person and those around them not smoke. Vaccinations to protect against viruses, such as hepatitis A and hepatitis B, that can further damage the liver should be given.
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It is difficult to predict how severely a liver will be affected. Liver function tests are followed over time.
Emma Wilson Admin
access_time 52 minutes ago
It is difficult to predict how severely a liver will be affected. Liver function tests are followed over time.
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Mason Rodriguez 46 minutes ago
Some patients may have minimal liver disease during their entire lifetime; however, a small number w...
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Madison Singh 34 minutes ago
We also have a frank discussion with the patient and family about what is involved in the evaluation...
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Some patients may have minimal liver disease during their entire lifetime; however, a small number will eventually require liver transplant. Cirrhosis or Chronic Liver Failure Cirrhosis or chronic liver failure can be caused by a number of the liver and biliary diseases listed in Clinical Services or sometimes appear without known cause. Our approach to pediatric patients with this problem is to start with a thorough history and physical examination and nutritional assessment.
Chloe Santos Moderator
access_time 42 minutes ago
Some patients may have minimal liver disease during their entire lifetime; however, a small number will eventually require liver transplant. Cirrhosis or Chronic Liver Failure Cirrhosis or chronic liver failure can be caused by a number of the liver and biliary diseases listed in Clinical Services or sometimes appear without known cause. Our approach to pediatric patients with this problem is to start with a thorough history and physical examination and nutritional assessment.
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Sofia Garcia 42 minutes ago
We also have a frank discussion with the patient and family about what is involved in the evaluation...
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We also have a frank discussion with the patient and family about what is involved in the evaluation for a life-saving liver transplant. Liver Cyst or Tumor There are multiple benign and malignant malformations or tumors that can occur in the liver of a child.
Isabella Johnson Member
access_time 15 minutes ago
We also have a frank discussion with the patient and family about what is involved in the evaluation for a life-saving liver transplant. Liver Cyst or Tumor There are multiple benign and malignant malformations or tumors that can occur in the liver of a child.
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Our approach begins with a thorough review of medical records and imaging studies. We work closely with our interventional radiologists and surgeons to establish an accurate diagnosis as quickly as possible. If the diagnosis is a malignant tumor, then we work with the pediatric oncologists and pediatric surgeons to decide the very best approach, which may include chemotherapy, radiation, embolization, surgical removal and/or liver transplantation.
Thomas Anderson Member
access_time 80 minutes ago
Our approach begins with a thorough review of medical records and imaging studies. We work closely with our interventional radiologists and surgeons to establish an accurate diagnosis as quickly as possible. If the diagnosis is a malignant tumor, then we work with the pediatric oncologists and pediatric surgeons to decide the very best approach, which may include chemotherapy, radiation, embolization, surgical removal and/or liver transplantation.
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Julia Zhang 22 minutes ago
Find a Doctor Specializing In: Alcoholic Liver Disease Biliary Tree Benign Liver Lesions Biliary Dis...
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Find a Doctor Specializing In: Alcoholic Liver Disease Biliary Tree Benign Liver Lesions Biliary Diseases Cirrhosis See More At Another Johns Hopkins Member Hospital: Howard County General Hospital Sibley Memorial Hospital Suburban Hospital Find a Treatment Center Johns Hopkins Children's Center Kennedy Krieger Institute Pediatric Gastroenterology Hepatology and Nutrition See More Find Additional Treatment Centers at: Howard County General Hospital Sibley Memorial Hospital Suburban Hospital Related Liver Health Common Characteristics of Liver Disease Liver Health: Infographic Common Liver Tests Request an Appointment Find a Doctor Find a Doctor See More Related Liver, Gallbladder and Pancreas Liver Health Chronic Liver Disease Common Characteristics of Liver Disease Liver, Gallbladder and Pancreas Liver Health: Infographic Related Topics
Henry Schmidt Member
access_time 17 minutes ago
Find a Doctor Specializing In: Alcoholic Liver Disease Biliary Tree Benign Liver Lesions Biliary Diseases Cirrhosis See More At Another Johns Hopkins Member Hospital: Howard County General Hospital Sibley Memorial Hospital Suburban Hospital Find a Treatment Center Johns Hopkins Children's Center Kennedy Krieger Institute Pediatric Gastroenterology Hepatology and Nutrition See More Find Additional Treatment Centers at: Howard County General Hospital Sibley Memorial Hospital Suburban Hospital Related Liver Health Common Characteristics of Liver Disease Liver Health: Infographic Common Liver Tests Request an Appointment Find a Doctor Find a Doctor See More Related Liver, Gallbladder and Pancreas Liver Health Chronic Liver Disease Common Characteristics of Liver Disease Liver, Gallbladder and Pancreas Liver Health: Infographic Related Topics
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Luna Park 5 minutes ago
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