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%Begin Leveraging Space to Advance Stem Cell Science and Medicine Skip to main content Close Select your preferred language English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog Menu Close Call 1-800-CEDARS-1 toggle search form Close Los Angeles, 30 December 2021 08:01 AM America/Los_Angeles Leveraging Space to Advance Stem Cell Science and Medicine Arun Sharma, PhD, leads a new research laboratory in the Cedars-Sinai Board of Governors Regenerative Medicine Institute, Smidt Heart Institute and Department of Biomedical Sciences. Photo by Cedars-Sinai. research scientist Arun Sharma, PhD A New Paper Led by Cedars-Sinai Identifies Opportunities Using Space-Based Technologies to Manufacture Stem Cells Create Advanced Disease Models and Expand 3D Printing Capabilities The secret to producing large batches of stem cells more efficiently may lie in the near-zero gravity conditions of space.
Grace Liu Member
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%Begin Leveraging Space to Advance Stem Cell Science and Medicine Skip to main content Close Select your preferred language English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog Menu Close Call 1-800-CEDARS-1 toggle search form Close Los Angeles, 30 December 2021 08:01 AM America/Los_Angeles Leveraging Space to Advance Stem Cell Science and Medicine Arun Sharma, PhD, leads a new research laboratory in the Cedars-Sinai Board of Governors Regenerative Medicine Institute, Smidt Heart Institute and Department of Biomedical Sciences. Photo by Cedars-Sinai. research scientist Arun Sharma, PhD A New Paper Led by Cedars-Sinai Identifies Opportunities Using Space-Based Technologies to Manufacture Stem Cells Create Advanced Disease Models and Expand 3D Printing Capabilities The secret to producing large batches of stem cells more efficiently may lie in the near-zero gravity conditions of space.
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Audrey Mueller 1 minutes ago
Scientists at Cedars-Sinai have found that microgravity has the potential to contribute to life-savi...
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Kevin Wang 1 minutes ago
“We are finding that spaceflight and microgravity is a desirable place for biomanufacturing becaus...
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Scientists at Cedars-Sinai have found that microgravity has the potential to contribute to life-saving advances on Earth by facilitating the rapid mass production of stem cells. A new paper, led by Cedars Sinai and published in the peer-reviewed journal Stem Cell Reports, highlights key opportunities discussed during the 2020 Biomanufacturing in Space Symposium to expand the manufacture of stem cells in space. Biomanufacturing—a type of stem cell production that uses biological materials such as microbes to produce substances and biomaterials suitable for use in preclinical, clinical, and therapeutic applications—can be more productive in microgravity conditions.
Alexander Wang Member
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Scientists at Cedars-Sinai have found that microgravity has the potential to contribute to life-saving advances on Earth by facilitating the rapid mass production of stem cells. A new paper, led by Cedars Sinai and published in the peer-reviewed journal Stem Cell Reports, highlights key opportunities discussed during the 2020 Biomanufacturing in Space Symposium to expand the manufacture of stem cells in space. Biomanufacturing—a type of stem cell production that uses biological materials such as microbes to produce substances and biomaterials suitable for use in preclinical, clinical, and therapeutic applications—can be more productive in microgravity conditions.
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“We are finding that spaceflight and microgravity is a desirable place for biomanufacturing because it confers a number of very special properties to biological tissues and biological processes that can help mass produce cells or other products in a way that you wouldn’t be able to do on Earth,” said stem cell biologist Arun Sharma, PhD, research scientist and head of a new research laboratory in the Cedars-Sinai Board of Governors Regenerative Medicine Institute, Smidt Heart Institute and Department of Biomedical Sciences. “The last two decades have seen remarkable advances in regenerative medicine and exponential advancement in space technologies enabling new opportunities to access and commercialize space,” he said.
Liam Wilson Member
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“We are finding that spaceflight and microgravity is a desirable place for biomanufacturing because it confers a number of very special properties to biological tissues and biological processes that can help mass produce cells or other products in a way that you wouldn’t be able to do on Earth,” said stem cell biologist Arun Sharma, PhD, research scientist and head of a new research laboratory in the Cedars-Sinai Board of Governors Regenerative Medicine Institute, Smidt Heart Institute and Department of Biomedical Sciences. “The last two decades have seen remarkable advances in regenerative medicine and exponential advancement in space technologies enabling new opportunities to access and commercialize space,” he said.
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Harper Kim 9 minutes ago
Attendees at the virtual space symposium in December identified more than 50 potential commercial op...
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Scarlett Brown 4 minutes ago
Investigators have found that once the body is exposed to low-gravity conditions for extended period...
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Attendees at the virtual space symposium in December identified more than 50 potential commercial opportunities for conducting biomanufacturing work in space, according to the Cedars-Sinai paper. The most promising fell into three categories: disease modeling, biofabrication, and stem-cell-derived products. The first, disease modeling, is used by scientists to study diseases and possible treatments by replicating full-function structures—whether using stem cells, organoids (miniature 3D structures grown from human stem cells that resemble human tissue), or other tissues.
Evelyn Zhang Member
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Attendees at the virtual space symposium in December identified more than 50 potential commercial opportunities for conducting biomanufacturing work in space, according to the Cedars-Sinai paper. The most promising fell into three categories: disease modeling, biofabrication, and stem-cell-derived products. The first, disease modeling, is used by scientists to study diseases and possible treatments by replicating full-function structures—whether using stem cells, organoids (miniature 3D structures grown from human stem cells that resemble human tissue), or other tissues.
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James Smith 15 minutes ago
Investigators have found that once the body is exposed to low-gravity conditions for extended period...
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Lily Watson 7 minutes ago
Another highly discussed topic at the symposium was biofabrication, which uses manufacturing process...
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Investigators have found that once the body is exposed to low-gravity conditions for extended periods of time, it experiences accelerated bone loss and aging. By developing disease models based on this accelerated aging process, research scientists can better understand the mechanisms of the aging process and disease progression. “Not only can this work help astronauts, but it can also lead to us manufacturing bone constructs or skeletal muscle constructs that could be applied to diseases like osteoporosis and other forms of accelerated bone aging and muscle wasting that people experience on Earth,” said Sharma, who is the corresponding author of the paper.
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Investigators have found that once the body is exposed to low-gravity conditions for extended periods of time, it experiences accelerated bone loss and aging. By developing disease models based on this accelerated aging process, research scientists can better understand the mechanisms of the aging process and disease progression. “Not only can this work help astronauts, but it can also lead to us manufacturing bone constructs or skeletal muscle constructs that could be applied to diseases like osteoporosis and other forms of accelerated bone aging and muscle wasting that people experience on Earth,” said Sharma, who is the corresponding author of the paper.
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Another highly discussed topic at the symposium was biofabrication, which uses manufacturing processes to produce materials like tissues and organs. 3D printing is one of the core biofabrication technologies. A major issue with producing these materials on Earth involves gravity-induced density, which makes it hard for cells to expand and grow.
Henry Schmidt Member
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Another highly discussed topic at the symposium was biofabrication, which uses manufacturing processes to produce materials like tissues and organs. 3D printing is one of the core biofabrication technologies. A major issue with producing these materials on Earth involves gravity-induced density, which makes it hard for cells to expand and grow.
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Kevin Wang 12 minutes ago
With the absence of gravity and density in space, scientists are hopeful that they can use 3D printi...
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Understanding some of the effects of spaceflight on stem cells can potentially lead to better ways t...
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With the absence of gravity and density in space, scientists are hopeful that they can use 3D printing to print unique shapes and products, like organoids or cardiac tissues, in a way that can’t be replicated on Earth. The third category has to do with the production of stem cells and understanding how some of their fundamental properties are influenced by microgravity. Some of these properties include potency, or the ability of a stem cell to renew itself, and differentiation, the ability for stem cells to turn into other cell types.
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With the absence of gravity and density in space, scientists are hopeful that they can use 3D printing to print unique shapes and products, like organoids or cardiac tissues, in a way that can’t be replicated on Earth. The third category has to do with the production of stem cells and understanding how some of their fundamental properties are influenced by microgravity. Some of these properties include potency, or the ability of a stem cell to renew itself, and differentiation, the ability for stem cells to turn into other cell types.
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Brandon Kumar 10 minutes ago
Understanding some of the effects of spaceflight on stem cells can potentially lead to better ways t...
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 “While we are still in the exploratory phase of some of this research, this is no longer...
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Understanding some of the effects of spaceflight on stem cells can potentially lead to better ways to manufacture large numbers of cells in the absence of gravity. Scientists from Cedars-Sinai will be sending stem cells into space early next year, in conjunction with NASA and a private contractor, Space Tango, to test whether it is possible to produce large batches in a low gravity environment.
Henry Schmidt Member
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Understanding some of the effects of spaceflight on stem cells can potentially lead to better ways to manufacture large numbers of cells in the absence of gravity. Scientists from Cedars-Sinai will be sending stem cells into space early next year, in conjunction with NASA and a private contractor, Space Tango, to test whether it is possible to produce large batches in a low gravity environment.
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Julia Zhang 14 minutes ago
 “While we are still in the exploratory phase of some of this research, this is no longer...
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It’s a tradition that took root in 1924, when Cedars-Sinai became home to the first electrocardiog...
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 “While we are still in the exploratory phase of some of this research, this is no longer in the realm of science fiction,” Sharma said. “Within the next five years we may see a scenario where we find cells or tissues that can be made in a way that is simply not possible here on Earth. And I think that’s extremely exciting.”   Related Stories RSS feed - Related Stories (opens in new window) View all headlines - Related Stories Fine-Tuning Organ-Chip Technology Scientists Develop a New Method to Better Visualize and Analyze Multicellular Interactions October 07, 2022 07:03 AM America/Los_Angeles A new method developed by scientists at Cedars-Sinai makes it easier to visualize the cell populations in organ chips, the technology that recapitulates true-to-life biology outside the body.Induced pluripotent stem cell and organ-chip technologies … Read more 15 Years of Heart Cedars-Sinai Marks A Decade-and-a-Half Since Founding the Smidt Heart Institute Leading to Breakthroughs in Cardiac Care Surgery and Disease Prevention October 03, 2022 06:01 AM America/Los_Angeles Pioneering heart care is a tradition at Cedars-Sinai.
Sophie Martin Member
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 “While we are still in the exploratory phase of some of this research, this is no longer in the realm of science fiction,” Sharma said. “Within the next five years we may see a scenario where we find cells or tissues that can be made in a way that is simply not possible here on Earth. And I think that’s extremely exciting.”   Related Stories RSS feed - Related Stories (opens in new window) View all headlines - Related Stories Fine-Tuning Organ-Chip Technology Scientists Develop a New Method to Better Visualize and Analyze Multicellular Interactions October 07, 2022 07:03 AM America/Los_Angeles A new method developed by scientists at Cedars-Sinai makes it easier to visualize the cell populations in organ chips, the technology that recapitulates true-to-life biology outside the body.Induced pluripotent stem cell and organ-chip technologies … Read more 15 Years of Heart Cedars-Sinai Marks A Decade-and-a-Half Since Founding the Smidt Heart Institute Leading to Breakthroughs in Cardiac Care Surgery and Disease Prevention October 03, 2022 06:01 AM America/Los_Angeles Pioneering heart care is a tradition at Cedars-Sinai.
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It’s a tradition that took root in 1924, when Cedars-Sinai became home to the first electrocardiogram machine in Los Angeles. The roots grew stronger in the 1970s, when two Cedars-Sinai … Read more Gut Gases Linked to Specific Types of Irritable Bowel Syndrome Cedars-Sinai Investigators Find Breath Testing IBS Patients May Lead to More Effective Treatment September 30, 2022 06:09 AM America/Los_Angeles A new study led by Cedars-Sinai investigators found using breath tests to identify gut gas profiles can potentially help lead to more personalized therapies for people diagnosed with irritable bowel syndrome (IBS). The most common gastrointestinal … Read more Show previous items Show next items Contact the Media Team Email: newsroom@cshs.org Contact Denise HeadyManager, Science Communications denise.heady@cshs.org 626‐378‐8184 Share this release Leveraging Space to Advance Stem Cell Science and Medicine Share on: Twitter Share on: Facebook Share on: LinkedIn Search Our Newsroom Social media Visit our Facebook page (opens in new window) Follow us on Twitter (opens in new window) Visit our Youtube profile (opens in new window) (opens in new window) Latest news 07 Oct 2022 - HealthDay: Black Women Less Likely to Get Laparoscopic Fibroid Surgeries 07 Oct 2022 - Faculty Publications: Sept. 29-Oct.
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It’s a tradition that took root in 1924, when Cedars-Sinai became home to the first electrocardiogram machine in Los Angeles. The roots grew stronger in the 1970s, when two Cedars-Sinai … Read more Gut Gases Linked to Specific Types of Irritable Bowel Syndrome Cedars-Sinai Investigators Find Breath Testing IBS Patients May Lead to More Effective Treatment September 30, 2022 06:09 AM America/Los_Angeles A new study led by Cedars-Sinai investigators found using breath tests to identify gut gas profiles can potentially help lead to more personalized therapies for people diagnosed with irritable bowel syndrome (IBS). The most common gastrointestinal … Read more Show previous items Show next items Contact the Media Team Email: [email protected] Contact Denise HeadyManager, Science Communications denise.heady@cshs.org 626‐378‐8184 Share this release Leveraging Space to Advance Stem Cell Science and Medicine Share on: Twitter Share on: Facebook Share on: LinkedIn Search Our Newsroom Social media Visit our Facebook page (opens in new window) Follow us on Twitter (opens in new window) Visit our Youtube profile (opens in new window) (opens in new window) Latest news 07 Oct 2022 - HealthDay: Black Women Less Likely to Get Laparoscopic Fibroid Surgeries 07 Oct 2022 - Faculty Publications: Sept. 29-Oct.
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