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% Digestive Diseases Research Publications  Cedars-Sinai Skip to content Close 
 Select your preferred language English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog English English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog Translation is unavailable for Internet Explorer Cedars-Sinai Home 1-800-CEDARS-1 1-800-CEDARS-1 Close Find a Doctor Locations Programs & Services Health Library Patient & Visitors Community My CS-Link RESEARCH clear Go Close Navigation Links Academics Faculty Development Community Engagement Calendar Research Research Areas Research Labs Departments & Institutes Find Clinical Trials Research Cores Research Administration Basic Science Research Clinical & Translational Research Center (CTRC) Technology & Innovations News & Breakthroughs Education Graduate Medical Education Continuing Medical Education Graduate School of Biomedical Sciences Professional Training Programs Medical Students Campus Life Office of the Dean Simulation Center Medical Library Program in the History of Medicine About Us All Education Programs Departments & Institutes Faculty Directory Digestive Diseases Research Center Back to Digestive Diseases Research Center About Us Membership Research Themes Cores & Services Pilot & Feasibility Program Enrichment Program Events Publications 
  Publications Investigators from the Digestive Diseases Research Center are frequently published in leading peer-reviewed journals. These selected publications provide insight into the breadth of research performed by the Digestive Diseases Research Center team.
% Digestive Diseases Research Publications Cedars-Sinai Skip to content Close Select your preferred language English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog English English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog Translation is unavailable for Internet Explorer Cedars-Sinai Home 1-800-CEDARS-1 1-800-CEDARS-1 Close Find a Doctor Locations Programs & Services Health Library Patient & Visitors Community My CS-Link RESEARCH clear Go Close Navigation Links Academics Faculty Development Community Engagement Calendar Research Research Areas Research Labs Departments & Institutes Find Clinical Trials Research Cores Research Administration Basic Science Research Clinical & Translational Research Center (CTRC) Technology & Innovations News & Breakthroughs Education Graduate Medical Education Continuing Medical Education Graduate School of Biomedical Sciences Professional Training Programs Medical Students Campus Life Office of the Dean Simulation Center Medical Library Program in the History of Medicine About Us All Education Programs Departments & Institutes Faculty Directory Digestive Diseases Research Center Back to Digestive Diseases Research Center About Us Membership Research Themes Cores & Services Pilot & Feasibility Program Enrichment Program Events Publications Publications Investigators from the Digestive Diseases Research Center are frequently published in leading peer-reviewed journals. These selected publications provide insight into the breadth of research performed by the Digestive Diseases Research Center team.
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Selected Publications Potdar AA, Dube S, Naito T, Li K, Botwin G, Haritunians T, Li D, Casero D, Yang S, Bilsborough J, Perrigoue JG, Denson LA, Daly M, Targan SR, Fleshner P, Braun J, Kugathasan S, Stappenbeck TS, McGovern DPB. Altered intestinal ACE2 levels are associated with inflammation, severe disease, and response to anti-cytokine therapy in inflammatory bowel disease. Gastroenterology.
Selected Publications Potdar AA, Dube S, Naito T, Li K, Botwin G, Haritunians T, Li D, Casero D, Yang S, Bilsborough J, Perrigoue JG, Denson LA, Daly M, Targan SR, Fleshner P, Braun J, Kugathasan S, Stappenbeck TS, McGovern DPB. Altered intestinal ACE2 levels are associated with inflammation, severe disease, and response to anti-cytokine therapy in inflammatory bowel disease. Gastroenterology.
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2021 Feb;160(3):809-822.e7. PMID: 33160965 Martin A, Ecklu-Mensah G, Ha C, Hendrick G, Layman DK, Gilbert J, Devkota S.
2021 Feb;160(3):809-822.e7. PMID: 33160965 Martin A, Ecklu-Mensah G, Ha C, Hendrick G, Layman DK, Gilbert J, Devkota S.
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Elijah Patel 1 minutes ago
Gut microbiota mediate the FGF21 adaptive stress response to chronic dietary protein restriction in ...
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Gut microbiota mediate the FGF21 adaptive stress response to chronic dietary protein restriction in mice. Nature Communications.
Gut microbiota mediate the FGF21 adaptive stress response to chronic dietary protein restriction in mice. Nature Communications.
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Joseph Kim 8 minutes ago
2021 Jun 22;12(1):3838. PMID: 34158480; PMCID: PMC8219803....
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2021 Jun 22;12(1):3838. PMID: 34158480; PMCID: PMC8219803.
2021 Jun 22;12(1):3838. PMID: 34158480; PMCID: PMC8219803.
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Ella Rodriguez 8 minutes ago
Gaddam S, Abboud Y, Oh J, Samaan JS, Nissen NN, Lu SC, Lo SK. Incidence of pancreatic cancer by age ...
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Gaddam S, Abboud Y, Oh J, Samaan JS, Nissen NN, Lu SC, Lo SK. Incidence of pancreatic cancer by age and sex in the U.S., 2000-2018.
Gaddam S, Abboud Y, Oh J, Samaan JS, Nissen NN, Lu SC, Lo SK. Incidence of pancreatic cancer by age and sex in the U.S., 2000-2018.
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Mia Anderson 4 minutes ago
JAMA. 2021; 326(20):2075-2077....
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JAMA. 2021; 326(20):2075-2077.
JAMA. 2021; 326(20):2075-2077.
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Brandon Kumar 7 minutes ago
PMID: 34689206; PMCID: PMC8543346. Wang Q, Kim SY, Matsushita H, Wang Z, Pandyarajan V, Matsuda M, O...
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Noah Davis 6 minutes ago
Proceedings Natl Acad Sci, USA. 2021;118(1):e2020868118. PMID: 33443222; PMCID: PMC7817133....
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PMID: 34689206; PMCID: PMC8543346. Wang Q, Kim SY, Matsushita H, Wang Z, Pandyarajan V, Matsuda M, Ohashi K, Tsuchiya T, Roh YS, Kiani C, Zhao Y, Chan M, Devkota S, Lu SC, Hayashi T, Carson DA, Seki E. Oral administration of PEGylated TLR7 ligand ameliorates alcohol-associated liver disease via the induction of IL-22.
PMID: 34689206; PMCID: PMC8543346. Wang Q, Kim SY, Matsushita H, Wang Z, Pandyarajan V, Matsuda M, Ohashi K, Tsuchiya T, Roh YS, Kiani C, Zhao Y, Chan M, Devkota S, Lu SC, Hayashi T, Carson DA, Seki E. Oral administration of PEGylated TLR7 ligand ameliorates alcohol-associated liver disease via the induction of IL-22.
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Proceedings Natl Acad Sci, USA. 2021;118(1):e2020868118. PMID: 33443222; PMCID: PMC7817133.
Proceedings Natl Acad Sci, USA. 2021;118(1):e2020868118. PMID: 33443222; PMCID: PMC7817133.
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Shiao SL, Kershaw K, Limon JL, You S, Yoon J, Ko E, Guarnerio J, Potdar A, McGovern DPB, Bose S, Dar T, Noe P, Lee J, Kubota Y, Maymi V, Davis M, Henson R, Choi R, Yang W, Tang J, Gargus M, Prince A, Zumsteg ZS, Underhill DM. Commensal bacteria and fungi differentially regulate tumor responses to radiation therapy. Cancer Cell.
Shiao SL, Kershaw K, Limon JL, You S, Yoon J, Ko E, Guarnerio J, Potdar A, McGovern DPB, Bose S, Dar T, Noe P, Lee J, Kubota Y, Maymi V, Davis M, Henson R, Choi R, Yang W, Tang J, Gargus M, Prince A, Zumsteg ZS, Underhill DM. Commensal bacteria and fungi differentially regulate tumor responses to radiation therapy. Cancer Cell.
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Mason Rodriguez 9 minutes ago
2021; 39(9):1202-1213. PMID:34329585. Barbier-Torres L, Murray B, Yang JW, Wang J, Matsuda M, Robins...
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Sophia Chen 25 minutes ago
Depletion of mitochondrial methionine adenosyltransferase α1 triggers mitochondrial dysfunction in ...
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2021; 39(9):1202-1213. PMID:34329585. Barbier-Torres L, Murray B, Yang JW, Wang J, Matsuda M, Robinson A, Binek A, Fan W, Fernández-Ramos D, Lopitz-Otsoa F, Luque-Urbano M, Millet O, Mavila N, Peng H, Ramani K, Gottlieb R, Sun Z, Liangpunsakul S, Seki E, Van Eyk J, Mato JM, Lu SC.
2021; 39(9):1202-1213. PMID:34329585. Barbier-Torres L, Murray B, Yang JW, Wang J, Matsuda M, Robinson A, Binek A, Fan W, Fernández-Ramos D, Lopitz-Otsoa F, Luque-Urbano M, Millet O, Mavila N, Peng H, Ramani K, Gottlieb R, Sun Z, Liangpunsakul S, Seki E, Van Eyk J, Mato JM, Lu SC.
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Audrey Mueller 19 minutes ago
Depletion of mitochondrial methionine adenosyltransferase α1 triggers mitochondrial dysfunction in ...
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Brandon Kumar 21 minutes ago
Ramani K, Robinson A, Berlind J, Fan W, Abeynayake A, Binek A, Barbier-Torres L, Noureddin M, Nissen...
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Depletion of mitochondrial methionine adenosyltransferase α1 triggers mitochondrial dysfunction in alcohol-associated liver disease. Nature Communication. 2022;13:557.
Depletion of mitochondrial methionine adenosyltransferase α1 triggers mitochondrial dysfunction in alcohol-associated liver disease. Nature Communication. 2022;13:557.
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Ramani K, Robinson A, Berlind J, Fan W, Abeynayake A, Binek A, Barbier-Torres L, Noureddin M, Nissen NN, Yidirim Z, Erbay E, Mato JM, Van Eyk J, Lu SC. S-adenosylmethionine inhibits la ribonucleoprotein domain family member 1 in murine liver and human liver cancer cells. Hepatology.
Ramani K, Robinson A, Berlind J, Fan W, Abeynayake A, Binek A, Barbier-Torres L, Noureddin M, Nissen NN, Yidirim Z, Erbay E, Mato JM, Van Eyk J, Lu SC. S-adenosylmethionine inhibits la ribonucleoprotein domain family member 1 in murine liver and human liver cancer cells. Hepatology.
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2022; 75(2):280-296. PMID: 34449924; PMCID: PMC8766892. Ha CWY, Martin A, Sepich-Poore GD, Shi B, Wang Y, Gouin K, Humphrey G, Sanders K, Ratnayake Y, Chan KSL, Hendrick G, Caldera JR, Arias C, Moskowitz JE, Ho Sui SJ, Yang S, Underhill D, Brady MJ, Knott S, Kaihara K, Steinbaugh MJ, Li H, McGovern DPB, Knight R, Fleshner P, Devkota S.
2022; 75(2):280-296. PMID: 34449924; PMCID: PMC8766892. Ha CWY, Martin A, Sepich-Poore GD, Shi B, Wang Y, Gouin K, Humphrey G, Sanders K, Ratnayake Y, Chan KSL, Hendrick G, Caldera JR, Arias C, Moskowitz JE, Ho Sui SJ, Yang S, Underhill D, Brady MJ, Knott S, Kaihara K, Steinbaugh MJ, Li H, McGovern DPB, Knight R, Fleshner P, Devkota S.
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Translocation of viable gut microbiota to mesenteric adipose drives formation of creeping fat in humans. Cell.
Translocation of viable gut microbiota to mesenteric adipose drives formation of creeping fat in humans. Cell.
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Ava White 28 minutes ago
2020 Oct 29;183(3):666-683.e17. doi: 10.1016/j.cell.2020.09.009....
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Zoe Mueller 18 minutes ago
Epub 2020 Sep 28. PMID: 32991841....
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2020 Oct 29;183(3):666-683.e17. doi: 10.1016/j.cell.2020.09.009.
2020 Oct 29;183(3):666-683.e17. doi: 10.1016/j.cell.2020.09.009.
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David Cohen 22 minutes ago
Epub 2020 Sep 28. PMID: 32991841....
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Epub 2020 Sep 28. PMID: 32991841.
Epub 2020 Sep 28. PMID: 32991841.
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Grace Liu 37 minutes ago
Limon JJ, Tang J, Li D, Wolf AJ, Michelsen KS, Funari V, Gargus M, Nguyen C, Sharma P, Maymi VI, Ili...
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Kevin Wang 43 minutes ago
Cell Host Microbe. 2019; 35(3):377-388....
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Limon JJ, Tang J, Li D, Wolf AJ, Michelsen KS, Funari V, Gargus M, Nguyen C, Sharma P, Maymi VI, Iliev ID, Skalski JH, Brown J, Landers C, Borneman J, Braun J, Targan SR, McGovern DPB, Underhill DM. Malassezia is associated with Crohn's disease and exacerbates colitis in mouse models.
Limon JJ, Tang J, Li D, Wolf AJ, Michelsen KS, Funari V, Gargus M, Nguyen C, Sharma P, Maymi VI, Iliev ID, Skalski JH, Brown J, Landers C, Borneman J, Braun J, Targan SR, McGovern DPB, Underhill DM. Malassezia is associated with Crohn's disease and exacerbates colitis in mouse models.
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Liam Wilson 29 minutes ago
Cell Host Microbe. 2019; 35(3):377-388....
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Cell Host Microbe. 2019; 35(3):377-388.
Cell Host Microbe. 2019; 35(3):377-388.
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Natalie Lopez 26 minutes ago
PMID: 30850233; PMCID: PMC6417942. Yang YM, Noureddin M, Liu C, Ohashi K, Kim SY, Ramnath D, Powell ...
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PMID: 30850233; PMCID: PMC6417942. Yang YM, Noureddin M, Liu C, Ohashi K, Kim SY, Ramnath D, Powell EE, Sweet MJ, Roh YS, Hsin IF, Deng N, Liu Z, Liang J, Mena E, Shouhed D, Schwabe RF, Jiang D, Lu SC, Noble PW, Seki E.
PMID: 30850233; PMCID: PMC6417942. Yang YM, Noureddin M, Liu C, Ohashi K, Kim SY, Ramnath D, Powell EE, Sweet MJ, Roh YS, Hsin IF, Deng N, Liu Z, Liang J, Mena E, Shouhed D, Schwabe RF, Jiang D, Lu SC, Noble PW, Seki E.
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Jack Thompson 94 minutes ago
Hyaluronan synthase 2-mediated hyaluronan production mediates Notch1 activation and liver fibrosis. ...
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Hyaluronan synthase 2-mediated hyaluronan production mediates Notch1 activation and liver fibrosis. Sci Transl Med. 2019 Jun 12;11(496):eaat9284.
Hyaluronan synthase 2-mediated hyaluronan production mediates Notch1 activation and liver fibrosis. Sci Transl Med. 2019 Jun 12;11(496):eaat9284.
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doi: 10.1126/scitranslmed.aat9284. PMID: 31189722. Have Questions or Need Help  If you have questions or would like to learn more about the CSDDRC, please contact Shelly Lu, MD, or Stephen Pandol, MD.
doi: 10.1126/scitranslmed.aat9284. PMID: 31189722. Have Questions or Need Help If you have questions or would like to learn more about the CSDDRC, please contact Shelly Lu, MD, or Stephen Pandol, MD.
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Victoria Lopez 6 minutes ago
Davis Building, Room 2097 8700 Beverly Blvd. Los Angeles, CA 90048 Call 310-423-9031 Send A Message ...
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Daniel Kumar 63 minutes ago
Digestive Diseases Research Publications Cedars-Sinai Skip to content Close Select your preferred...
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Davis Building, Room 2097 8700 Beverly Blvd. Los Angeles, CA 90048 Call 310-423-9031 Send A Message Please ensure Javascript is enabled for purposes of website accessibility
Davis Building, Room 2097 8700 Beverly Blvd. Los Angeles, CA 90048 Call 310-423-9031 Send A Message Please ensure Javascript is enabled for purposes of website accessibility
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