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Cedars-Sinai Research Identifies Gut Gas Linked to Diarrhea Ali Rezaie, MD, administers a breath test at Cedars-Sinai. Photo by Cedars-Sinai.
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Lily Watson 2 minutes ago
By Cedars-Sinai
Findings on Hydrogen Sulfide and Development of New Breath Test Expected to Impr...
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Natalie Lopez 1 minutes ago
The presence of methane gas often explains the symptoms but has not been linked to diarrhea in many ...
By Cedars-Sinai
Findings on Hydrogen Sulfide and Development of New Breath Test Expected to Improve the Diagnosis and Treatment of Patients With Debilitating Gastrointestinal Disorders Cedars-Sinai investigators have for the first time identified a gas produced in gut that could improve the diagnosis and treatment of patients with two common intestinal illnesses-small intestine bacterial overgrowth (SIBO) and irritable bowel syndrome (IBS). Patients complaining of pain, bloating, diarrhea, constipation and other gastrointestinal distress are routinely given a breath test to determine if they have small intestine bacterial overgrowth, an excess of certain bacteria in the small intestine.
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Christopher Lee 1 minutes ago
The presence of methane gas often explains the symptoms but has not been linked to diarrhea in many ...
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Scarlett Brown 1 minutes ago
"This is a game-changer because we now see the full picture of fermentation gases, and it is hy...
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Isaac Schmidt Member
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12 minutes ago
Saturday, 03 May 2025
The presence of methane gas often explains the symptoms but has not been linked to diarrhea in many patients. Now a large-scale clinical trial has identified the presence of another gut gas-hydrogen sulfide-among these patients who experience diarrhea.
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Emma Wilson 9 minutes ago
"This is a game-changer because we now see the full picture of fermentation gases, and it is hy...
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Zoe Mueller 6 minutes ago
" "This is a game-changer because we now see the full picture of fermentation gases, and i...
"This is a game-changer because we now see the full picture of fermentation gases, and it is hydrogen sulfide that appears to be linked to diarrhea," said Mark Pimentel, MD, executive director of the Medically Associated Science and Technology (MAST) Program at Cedars-Sinai. "We knew something was missing from the conventional test."
Pimentel's team unveiled the new study results at the Digestive Disease Week conference in Washington D.C., where Cedars-Sinai investigators shared other research findings as well. Pimentel, the study's senior author, said the new research by his team has led to the development of a new four-gas breath test device that should be available to patients by the end of the year.
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Alexander Wang 1 minutes ago
" "This is a game-changer because we now see the full picture of fermentation gases, and i...
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Evelyn Zhang 2 minutes ago
At this time, there is no financial value associated with the filed patent, however, it is possible ...
" "This is a game-changer because we now see the full picture of fermentation gases, and it is hydrogen sulfide that appears to be linked to diarrhea." Mark Pimentel, MD„ "This novel device will allow physicians to better diagnose and treat small intestine bacterial overgrowth in patients. And the new tool will also be useful in screening for IBS-the most common GI disorder in the world," he said. Disclosure: Mark Pimentel, MD, Ali Rezaie, MD and Kapil Gupta, MD are involved in the clinical trial and named on the patent application for the new breath test device.
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Henry Schmidt Member
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At this time, there is no financial value associated with the filed patent, however, it is possible that the investigators could receive royalty income should the patent be licensed in the future. Cedars-Sinai investigations presented results of a variety of other studies at Digestive Disease Week, including the following:Gender differences in inflammatory bowel disease: Gender differences in the genetic underpinnings of inflammatory bowel disease (IBD) are not well understood. Researchers at Cedars-Sinai's Inflammatory Bowel and Immunobiology Research Institute, directed by Stephan R.
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Zoe Mueller 5 minutes ago
Targan, MD, have identified gender-specific associations in patients with Crohn's disease and u...
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Madison Singh 1 minutes ago
The investigation was led by research scientist Talin Haritunians, PhD and Dermot P. McGovern, MD, P...
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Madison Singh Member
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Targan, MD, have identified gender-specific associations in patients with Crohn's disease and ulcerative colitis, the two most prominent forms of IBD. The results of the genetic research suggest a closer look at gender may provide important insights into the severity with which IBD develops in male and female patients.
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Kevin Wang Member
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The investigation was led by research scientist Talin Haritunians, PhD and Dermot P. McGovern, MD, PhD, director of Translational Research in the Inflammatory Bowel and Immunobiology Research Institute."Creeping Fat" around intestines of IBD patients: Most Crohn's disease patients develop what is known as "creeping fat" around sites of inflammation in the intestines.
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Kevin Wang 28 minutes ago
Does this phenomenon protect the intestines or lead to further disease complications? In a study of ...
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Ethan Thomas Member
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Saturday, 03 May 2025
Does this phenomenon protect the intestines or lead to further disease complications? In a study of the make-up and behavior of "creeping fat," investigators led by Suzanne Devkota, PhD, found that specific gut bacteria migrate to the fat tissue outside of the gut and stimulate that area of fat to grow.
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Andrew Wilson 1 minutes ago
While this process may initially be a protective response to wounds in the intestine caused by Crohn...
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Dylan Patel Member
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Saturday, 03 May 2025
While this process may initially be a protective response to wounds in the intestine caused by Crohn's, the extra fat can eventually cause fibrosis, making the disease worse.Mobile health and food symptom tracker: How good are we at accurately associating what we eat with the development of gut trouble? Research led by Brennan M.
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William Brown Member
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Saturday, 03 May 2025
Spiegel, MD, director of Health Services Research at Cedars-Sinai, tested a new questionnaire called the Food and Symptom Tracker (FAST). Investigators successfully validated the FAST questionnaire against existing measures.
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Andrew Wilson 5 minutes ago
The findings suggest that FAST can be used as part of digital health apps for patients to more accur...
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Aria Nguyen 5 minutes ago
29-Oct. 6 07 Oct 2022 - Fine-Tuning Organ-Chip Technology 06 Oct 2022 - KCRW: Want New Omicron Boost...
The findings suggest that FAST can be used as part of digital health apps for patients to more accurately track their food-specific gastrointestinal symptoms. Photo by Cedars-Sinai
Contact the Media Team Email: [email protected]
Contact Laura Coverson laura.coverson@cshs.org
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Cedars-Sinai Research Identifies Gut Gas Linked to Diarrhea Skip to main content Close
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By Cedars-Sinai
Findings on Hydrogen Sulfide and Development of New Breath Test Expected to Impr...