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About Acute Flaccid Myelitis
Medically reviewed by Heidi Moawad, M.D. — By Jill Seladi-Schulman, Ph.D.
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Mason Rodriguez 1 minutes ago
on September 16, 2022Acute flaccid myelitis (AFM) is a rare neurological condition that can cause pa...
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Sofia Garcia 1 minutes ago
As of writing, the Centers for Disease Control and Prevention (CDC) reports that there have been 13 ...
on September 16, 2022Acute flaccid myelitis (AFM) is a rare neurological condition that can cause paralysis. It mainly occurs in children, but it can occur in adults, too.
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Aria Nguyen 5 minutes ago
As of writing, the Centers for Disease Control and Prevention (CDC) reports that there have been 13 ...
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Daniel Kumar Member
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9 minutes ago
Thursday, 08 May 2025
As of writing, the Centers for Disease Control and Prevention (CDC) reports that there have been 13 confirmed cases of AFM in 2022. A total of 692 cases have been reported since the CDC began tracking the condition in 2014. Below, we’ll go into more detail about AFM, including its symptoms and causes, as well as how doctors diagnose and treat it.
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David Cohen 6 minutes ago
What is acute flaccid myelitis
AFM is a rare neurological condition that impacts the nervo...
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Emma Wilson Admin
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20 minutes ago
Thursday, 08 May 2025
What is acute flaccid myelitis
AFM is a rare neurological condition that impacts the nervous system. The most common symptom of AFM is limb weakness or paralysis that comes on suddenly. People with AFM have areas of damage in the gray matter of the spinal cord that doctors can see using an MRI.
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Audrey Mueller Member
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Thursday, 08 May 2025
The gray matter is important for things like muscle movement and gathering sensory information. The damage that occurs due to AFM can be permanent and life threatening.
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Christopher Lee 2 minutes ago
This makes AFM a medical emergency. According to the CDC, 98% of people with AFM get hospital admitt...
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Madison Singh 23 minutes ago
In addition to fever, other early symptoms can include a runny or stuffy nose, cough, or sore throat...
This makes AFM a medical emergency. According to the CDC, 98% of people with AFM get hospital admittance, and 54% go to the intensive care unit (ICU).
Symptoms of acute flaccid myelitis
Many people who develop AFM have an illness with fever about 1 to 10 days before any symptom onset.
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Luna Park Member
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Thursday, 08 May 2025
In addition to fever, other early symptoms can include a runny or stuffy nose, cough, or sore throat. When the symptoms of AFM develop, they can include:limb weakness or paralysis that comes on suddenlyloss of reflexespain in the limbs, neck, or backdifficulty with movementfacial weakness, which can cause drooping eyelids or difficulty moving the eyesdifficulty talking or swallowing
Fever and headache are also common symptoms of AFM. AFM is a medical emergency.
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Amelia Singh 14 minutes ago
If you or a child experiences any of the symptoms above, call 911 or go to the emergency room immedi...
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Elijah Patel Member
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Thursday, 08 May 2025
If you or a child experiences any of the symptoms above, call 911 or go to the emergency room immediately.
Causes of acute flaccid myelitis
The exact cause of AFM is still unknown. However, an increase in the occurrence of AFM often links to a rise in illnesses due to the enterovirus EV-D68, which can cause a cold-like illness.
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Isabella Johnson 7 minutes ago
Indeed, many people who develop AFM report having an illness with fever before their symptoms come o...
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William Brown 24 minutes ago
Several types of enteroviruses can cause the common cold, while others cause hand, foot, and mouth d...
Indeed, many people who develop AFM report having an illness with fever before their symptoms come on. Most cases of AFM happen between August and November, a time of the year when many enteroviruses like EV-D68 circulate. Enteroviruses are a diverse group of viruses.
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Brandon Kumar 22 minutes ago
Several types of enteroviruses can cause the common cold, while others cause hand, foot, and mouth d...
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Liam Wilson Member
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Thursday, 08 May 2025
Several types of enteroviruses can cause the common cold, while others cause hand, foot, and mouth disease and polio. We don’t know how exactly EV-D68 may cause AFM. It’s possible that the damage in the gray matter, which leads to the symptoms of AFM, could be due to the virus itself, the immune system’s response to the infection, or both.
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Emma Wilson Admin
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Thursday, 08 May 2025
Many people that get AFM are children. A 2020 research review noted that the average age at diagnosis is 6.3 years old.
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Chloe Santos 40 minutes ago
Less than 15% of people who develop AFM are adults.
Is AFM related to polio
Polio and AFM ...
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Elijah Patel 43 minutes ago
However, experts have not detected poliovirus in samples from people with AFM. According to the CDC,...
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Luna Park Member
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12 minutes ago
Thursday, 08 May 2025
Less than 15% of people who develop AFM are adults.
Is AFM related to polio
Polio and AFM cause very similar symptoms. Additionally, EV-D68 and poliovirus are both enteroviruses.
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Lucas Martinez 3 minutes ago
However, experts have not detected poliovirus in samples from people with AFM. According to the CDC,...
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Jack Thompson 6 minutes ago
Since the introduction of the polio vaccine, experts effectively eliminated polio in the United Stat...
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Lily Watson Moderator
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13 minutes ago
Thursday, 08 May 2025
However, experts have not detected poliovirus in samples from people with AFM. According to the CDC, experts adopted the term “AFM” in 2014. It refers to a polio-like illness that has an unknown cause.
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Thomas Anderson Member
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Thursday, 08 May 2025
Since the introduction of the polio vaccine, experts effectively eliminated polio in the United States. In rare cases, travelers who’ve contracted it have brought it into the country.
Diagnosis for acute flaccid myelitis
The diagnosis of AFM can be tricky.
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Grace Liu Member
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60 minutes ago
Thursday, 08 May 2025
Not only is it rare overall, but its symptoms can be similar to other neurological conditions, including, but not limited to:polioGuillain-Barre syndrometransverse myelitismultiple sclerosisacute disseminated encephalomyelitis
Getting a thorough medical history is important. In addition to evaluating your symptoms, a doctor will note things like age, time of year, and if you have a recent history of illness with fever.
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Chloe Santos 24 minutes ago
They can also do the following tests to help confirm a diagnosis of AFM:Physical exam: During this e...
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Alexander Wang 8 minutes ago
It can help your doctor to look for signs of inflammation in your spinal cord.Nerve conduction tests...
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Ava White Moderator
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32 minutes ago
Thursday, 08 May 2025
They can also do the following tests to help confirm a diagnosis of AFM:Physical exam: During this exam, your doctor will look for areas with reduced muscle tone and weakness. They’ll also check your reflexes.MRI scan: An MRI scan uses radio waves and strong magnets to create images of the inside of your body. Doctors can use it to look for signs of damage in your spinal cord.Cerebrospinal fluid analysis: This test uses a sample of cerebrospinal fluid that a doctor collects using a lumbar puncture.
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James Smith Moderator
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Thursday, 08 May 2025
It can help your doctor to look for signs of inflammation in your spinal cord.Nerve conduction tests: These tests help check the signaling along your nerves. They can help a doctor figure out where along your nerves the weakness or paralysis starts.Laboratory tests: Additional laboratory tests of blood, stool, or respiratory samples can aid your doctor in confirming or ruling out other health conditions as the causes of your symptoms.
Treatment for acute flaccid myelitis
There’s currently no standard treatment for AFM.
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Amelia Singh Moderator
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36 minutes ago
Thursday, 08 May 2025
Further, according to a 2020 research review, only observational studies on treatment outcomes for AFM are currently available. Experts need to perform further research to find effective treatments for the condition.
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Grace Liu Member
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76 minutes ago
Thursday, 08 May 2025
Right now, the treatment of AFM focuses on providing supportive care, such as:monitoring vital signs like respiratory rate, heart rate, and blood pressuremanaging painstabilizing respiratory, heart, and bowel functionproviding respiratory support with a ventilator, if necessarypreventing complications from being immobile, such as bed sores and blood clots
It’s also possible that your doctor may choose to use other types of treatments as well, such as:intravenous immunoglobulincorticosteroidsplasmapheresis
These treatments can help suppress the immune system to reduce an immune response that could be a factor in an underlying condition. However, according to CDC guidance, there’s currently no evidence for or against the use of these treatments for AFM.
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Nathan Chen 38 minutes ago
Preventing acute flaccid myelitis
Since experts don’t yet know the exact cause of AFM, th...
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Ethan Thomas Member
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Thursday, 08 May 2025
Preventing acute flaccid myelitis
Since experts don’t yet know the exact cause of AFM, there’s currently no way to prevent it completely. It’s unclear why some people develop AFM and others do not. However, since AFM links with a viral infection, there are some general steps that you can take to help reduce your risk, such as:washing your hands frequently with soap and waterrefraining from touching your eyes, mouth, or nose with unwashed handscleaning frequently touched surfaces in your home regularly, such as doorknobs and light switchesavoiding close physical contact with people who are sick
Outlook for acute flaccid myelitis
AFM can lead to permanent muscle weakness or paralysis.
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Natalie Lopez 2 minutes ago
Although the outlook can vary by individual, generally speaking, a full recovery is uncommon. For ex...
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Madison Singh 81 minutes ago
During an average follow-up of 9 months, 38% reported persistent limb weakness. A small 2017 study i...
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Emma Wilson Admin
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84 minutes ago
Thursday, 08 May 2025
Although the outlook can vary by individual, generally speaking, a full recovery is uncommon. For example, a small 2015 study involved a follow-up with 45 people who had experienced AFM.
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Ryan Garcia 7 minutes ago
During an average follow-up of 9 months, 38% reported persistent limb weakness. A small 2017 study i...
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Ella Rodriguez Member
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110 minutes ago
Thursday, 08 May 2025
During an average follow-up of 9 months, 38% reported persistent limb weakness. A small 2017 study involved a follow-up with 8 children a year after they had developed AFM. Although experts observed some improvements over time, 6 children had continuing problems with movement a year later.
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Ella Rodriguez 80 minutes ago
Whether or not experts detect enterovirus in samples may also affect the outlook, according to a sma...
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Emma Wilson Admin
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115 minutes ago
Thursday, 08 May 2025
Whether or not experts detect enterovirus in samples may also affect the outlook, according to a small 2020 study. Compared with patients who tested negative for enterovirus, those who tested positive had a higher likelihood of:admission to the ICUweakness or paralysis affecting all four limbsbulbar palsy, which can cause symptoms like trouble breathing and difficulty swallowing or speakingproblems with bowel or bladder functioncardiovascular instability, which can include atypical heart rate or blood pressure
Doctors will likely recommend physical therapy, occupational therapy, or both if you’ve had AFM. Physical therapy focuses on improving strength and flexibility, while occupational therapy helps you to learn ways to do daily activities.
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Brandon Kumar 22 minutes ago
The bottom line
AFM is a rare neurological condition that can lead to permanent muscle weak...
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Alexander Wang 32 minutes ago
However, why some people develop AFM while others do not is currently unclear. AFM is a medical emer...
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Charlotte Lee Member
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24 minutes ago
Thursday, 08 May 2025
The bottom line
AFM is a rare neurological condition that can lead to permanent muscle weakness or paralysis. It mainly affects children, but adults can develop the condition as well. Experts generally believe that a viral infection may trigger AFM, specifically with the enterovirus EV-D68.
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Henry Schmidt Member
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However, why some people develop AFM while others do not is currently unclear. AFM is a medical emergency.
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Ella Rodriguez Member
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If you or a child experiences limb weakness or paralysis that comes on suddenly, get emergency medical care. Last medically reviewed on September 16, 2022
How we vetted this article
SourcesHistoryHealthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations.
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We avoid using tertiary references. You can learn more about how we ensure our content is accurate a...
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(2020). Acute flaccid myelitis: Current status and diagnostic challenges. ncbi.nlm.nih.gov/pmc/a...
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Christopher Lee Member
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We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.Acute flaccid myelitis (AFM). (2022). cdc.gov/acute-flaccid-myelitis/index.htmlFang X, et al.
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(2020). Acute flaccid myelitis: Current status and diagnostic challenges. ncbi.nlm.nih.gov/pmc/a...
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(2019). Acute flaccid myelitis: A clinical overview for 2019. mayoclinicproceedings.org/article/...
(2022). cdc.gov/globalhealth/immunization/Martin JA, et al. (2017).
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Outcomes of Colorado children with acute flaccid myelitis at 1 year. ncbi.nlm.nih.gov/pmc/articl...
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(2020). cdc.gov/non-polio-enterovirus/index.htmlVan Haren K, et al. (2015). Acute flaccid myelit...
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Outcomes of Colorado children with acute flaccid myelitis at 1 year. ncbi.nlm.nih.gov/pmc/articles/PMC5501931/Murphy OC, et al. (2020). Acute flaccid myelitis: Cause, diagnosis, and management. ncbi.nlm.nih.gov/pmc/articles/PMC7909727/Non-polio enterovirus.
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(2020). cdc.gov/non-polio-enterovirus/index.htmlVan Haren K, et al. (2015). Acute flaccid myelit...
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(2022). cdc.gov/vitalsigns/index.htmlYea C, et al. (2020)....
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(2020). cdc.gov/non-polio-enterovirus/index.htmlVan Haren K, et al. (2015). Acute flaccid myelitis of unknown etiology in California, 2012-2015. jamanetwork.com/journals/jama/fullarticle/2478202Vital signs.
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Association of outcomes in acute flaccid myelitis with identification of enterovirus at presentation...
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(2022). cdc.gov/vitalsigns/index.htmlYea C, et al. (2020).
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Association of outcomes in acute flaccid myelitis with identification of enterovirus at presentation: A Canadian, nationwide, longitudinal study. linkinghub.elsevier.com/retrieve/pii/S2352-4642(20)30176-0Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Current Version
Sep 16, 2022
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Share this articleMedically reviewed by Heidi Moawad, M.D.
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— By Jill Seladi-Schulman, Ph.D. on September 16, 2022
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Acute Flaccid Myelitis: Symptoms, Causes, and Treatment Health ConditionsFeaturedBreast CancerIBD Mi...
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on September 16, 2022Acute flaccid myelitis (AFM) is a rare neurological condition that can cause pa...